Roland Kanaar, PhD

Affiliations: 
Genetics and Cell Biology Erasmus Medical Center Rotterdam, Rotterdam, Netherlands 
Area:
DNA Repair
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"Roland Kanaar"
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Parents

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Pieter van de Putte grad student 1988 Leiden
 (Site-specific DNA inversion in the genome of bacteriophage Mu : a topological analysis)

Children

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Devashish Das post-doc 2009-2011 Erasmus MC
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Publications

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Heemskerk T, Groenendijk C, Rovituso M, et al. (2025) Position in proton Bragg curve influences DNA damage complexity and survival in head and neck cancer cells. Clinical and Translational Radiation Oncology. 51: 100908
Heemskerk T, van de Kamp G, Rovituso M, et al. (2024) Enhanced radiosensitivity of head and neck cancer cells to proton therapy via hyperthermia-induced homologous recombination deficiency. Clinical and Translational Radiation Oncology. 51: 100898
van de Kamp G, Heemskerk T, Kanaar R, et al. (2024) Synergistic Roles of Non-Homologous End Joining and Homologous Recombination in Repair of Ionizing Radiation-Induced DNA Double Strand Breaks in Mouse Embryonic Stem Cells. Cells. 13
Paul MW, Aaron J, Wait E, et al. (2024) Distinct mobility patterns of BRCA2 molecules at DNA damage sites. Nucleic Acids Research
Muniesa-Vargas A, Davó-Martínez C, Ribeiro-Silva C, et al. (2024) Persistent TFIIH binding to non-excised DNA damage causes cell and developmental failure. Nature Communications. 15: 3490
Ghouil R, Miron S, Sato K, et al. (2023) BRCA2-HSF2BP oligomeric ring disassembly by BRME1 promotes homologous recombination. Science Advances. 9: eadi7352
Heemskerk T, van de Kamp G, Essers J, et al. (2023) Multi-scale cellular imaging of DNA double strand break repair. Dna Repair. 131: 103570
van de Kamp G, Heemskerk T, Kanaar R, et al. (2021) DNA Double Strand Break Repair Pathways in Response to Different Types of Ionizing Radiation. Frontiers in Genetics. 12: 738230
Paul MW, Sidhu A, Liang Y, et al. (2021) Role of BRCA2 DNA-binding and C-terminal domain on its mobility and conformation in DNA repair. Elife. 10
Paul MW, Sidhu A, Liang Y, et al. (2021) Role of BRCA2 DNA-binding and C-terminal domain on its mobility and conformation in DNA repair. Elife. 10
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