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Steven L. Nail

Affiliations: 
Purdue University, West Lafayette, IN, United States 
Area:
Pharmaceutical Chemistry
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"Steven Nail"
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Xuhong Li grad student 2002 Purdue
John J. Schwegman grad student 2004 Purdue

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Fang R, Bogner RH, Nail SL, et al. (2020) Stability of Freeze-Dried Protein Formulations: Contributions of Ice Nucleation Temperature and Residence Time in the Freeze-Concentrate. Journal of Pharmaceutical Sciences
Iyer LK, Sacha GA, Moorthy BS, et al. (2016) Process and Formulation Effects on Protein Structure in Lyophilized Solids Using Mass Spectrometric Methods. Journal of Pharmaceutical Sciences
Schwegman JJ, Carpenter JF, Nail SL. (2009) Evidence of partial unfolding of proteins at the ice/freeze-concentrate interface by infrared microscopy. Journal of Pharmaceutical Sciences. 98: 3239-46
Cochran T, Nail SL. (2009) Ice nucleation temperature influences recovery of activity of a model protein after freeze drying. Journal of Pharmaceutical Sciences. 98: 3495-8
Schwegman JJ, Carpenter JF, Nail SL. (2007) Infrared microscopy for in situ measurement of protein secondary structure during freezing and freeze-drying. Journal of Pharmaceutical Sciences. 96: 179-95
Tang XC, Nail SL, Pikal MJ. (2006) Evaluation of manometric temperature measurement (MTM), a process analytical technology tool in freeze drying, part III: heat and mass transfer measurement. Aaps Pharmscitech. 7: 97
Li X, Nail SL. (2006) Nuclear magnetic resonance imaging of freeze-drying. Journal of Pharmaceutical Sciences. 95: 2516-25
Liu W, Wang DQ, Nail SL. (2005) Freeze-drying of proteins from a sucrose-glycine excipient system: effect of formulation composition on the initial recovery of protein activity. Aaps Pharmscitech. 6: E150-7
Tang XC, Nail SL, Pikal MJ. (2005) Freeze-drying process design by manometric temperature measurement: design of a smart freeze-dryer. Pharmaceutical Research. 22: 685-700
Li X, Nail SL. (2005) Kinetics of glycine crystallization during freezing of sucrose/glycine excipient systems. Journal of Pharmaceutical Sciences. 94: 625-31
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