Robert Shapiro

Affiliations: 
New York University, New York, NY, United States 
Area:
Organic and bioorganic chemistry
Website:
http://www.robertshapiro.org/
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"Robert Shapiro"
Mean distance: 6.94
 
SNBCP

Parents

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Robert B. Woodward grad student 1959 Harvard
 (I. Experiments on the synthesis of colchicine. II. A new method for pyrrole synthesis)

Children

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Lei Jia grad student 2002-2007 NYU (Computational Biology Tree)
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Publications

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Troll W, Shapiro R. (2011) Action of Environmental Agents on Nucleic Acids and Their Metabolism Comprehensive Physiology
Donny-Clark K, Shapiro R, Broyde S. (2009) Accommodation of an N-(deoxyguanosin-8-yl)-2-acetylaminofluorene adduct in the active site of human DNA polymerase iota: Hoogsteen or Watson-Crick base pairing? Biochemistry. 48: 7-18
Ding S, Shapiro R, Cai Y, et al. (2008) Conformational properties of equilenin-DNA adducts: stereoisomer and base effects. Chemical Research in Toxicology. 21: 1064-73
Ding S, Shapiro R, Geacintov NE, et al. (2007) 4-hydroxyequilenin-adenine lesions in DNA duplexes: stereochemistry, damage site, and structure. Biochemistry. 46: 182-91
Zhang L, Rechkoblit O, Wang L, et al. (2006) Mutagenic nucleotide incorporation and hindered translocation by a food carcinogen C8-dG adduct in Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4): modeling and dynamics studies. Nucleic Acids Research. 34: 3326-37
Jia L, Shafirovich V, Shapiro R, et al. (2006) Flexible 5-guanidino-4-nitroimidazole DNA lesions: structures and thermodynamics. Biochemistry. 45: 6644-55
Ding S, Shapiro R, Geacintov NE, et al. (2005) Equilenin-derived DNA adducts to cytosine in DNA duplexes: structures and thermodynamics. Biochemistry. 44: 14565-76
Jia L, Shafirovich V, Shapiro R, et al. (2005) Structural and thermodynamic features of spiroiminodihydantoin damaged DNA duplexes. Biochemistry. 44: 13342-53
Zhang L, Shapiro R, Broyde S. (2005) Molecular dynamics of a food carcinogen-DNA adduct in a replicative DNA polymerase suggest hindered nucleotide incorporation and extension. Chemical Research in Toxicology. 18: 1347-63
Jia L, Shafirovich V, Shapiro R, et al. (2005) Spiroiminodihydantoin lesions derived from guanine oxidation: structures, energetics, and functional implications. Biochemistry. 44: 6043-51
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