Joel M. Gottesfeld, Ph.D.

Affiliations: 
1978- Cell and Molecular Biology Scripps Research Institute, La Jolla, La Jolla, CA, United States 
Area:
Biochemistry, Molecular Biology
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Parents

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James Frederick Bonner grad student 1972-1975 Caltech

Children

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Larry S. Millstein grad student 1987 UCSD
Rachel L. Winston grad student 2000 Scripps Institute
Amy C. Beltran grad student 2003 Scripps Institute
Christian Melander grad student 2002-2004 The Scripps Research Institute, La Jolla, CA (Microtree)
Sherman Ku grad student 2006-2010 Scripps Institute
Jiun-I Lai grad student 2011-2016 Scripps Institute
Ryan S. Burnett post-doc 2002-2008 (Neurotree)

Collaborators

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Peter B. Dervan collaborator 1995- Caltech
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Publications

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Rodden LN, Chutake YK, Gilliam K, et al. (2021) Methylated and unmethylated epialleles support variegated epigenetic silencing in Friedreich ataxia. Human Molecular Genetics
Gottesfeld JM. (2019) Molecular Mechanisms and Therapeutics for the GAA·TTC Expansion Disease Friedreich Ataxia. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics
Gottesfeld JM. (2019) Milestones in transcription and chromatin published in the . The Journal of Biological Chemistry. 294: 1652-1660
Lai JI, Nachun D, Petrosyan L, et al. (2018) Transcriptional profiling of isogenic Friedreich ataxia neurons and effect of an HDAC inhibitor on disease signatures. The Journal of Biological Chemistry
Gottesfeld JM, Carey MF. (2018) Introduction to Thematic Minireview Series: Chromatin and Transcription. The Journal of Biological Chemistry
Soragni E, Petrosyan L, Rinkoski TA, et al. (2018) Repeat-Associated Non-ATG (RAN) Translation in Fuchs' Endothelial Corneal Dystrophy. Investigative Ophthalmology & Visual Science. 59: 1888-1896
Lai JI, Leman LJ, Ku S, et al. (2017) Cyclic tetrapeptide HDAC inhibitors as potential therapeutics for spinal muscular atrophy: Screening with iPSC-derived neuronal cells. Bioorganic & Medicinal Chemistry Letters
Soragni E, Gottesfeld JM. (2016) Translating HDAC inhibitors in Friedrich's ataxia. Expert Opinion On Orphan Drugs. 4: 961-970
Jia H, Wang Y, Morris CD, et al. (2016) The Effects of Pharmacological Inhibition of Histone Deacetylase 3 (HDAC3) in Huntington's Disease Mice. Plos One. 11: e0152498
Soragni E, Gottesfeld JM. (2016) Translating HDAC inhibitors in Friedreich’s ataxia Expert Opinion On Orphan Drugs. 4: 961-970
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