John Hampton Griffin

Affiliations: 
Numerate, Inc 
Area:
organic and biological chemistry
Website:
http://www.numerate.com/company/leadership/john_griffin.php
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"John Griffin"
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Peter B. Dervan grad student 1989 Caltech
 (Structure-, stereochemistry-, and metal-regulated DNA binding/cleaving molecules)
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Publications

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Deguchi H, Morla S, Griffin JH. (2020) Novel Blood Coagulation Molecules: Skeletal Muscle Myosin and Cardiac Myosin. Journal of Thrombosis and Haemostasis : Jth
von Drygalski A, Bhat V, Gale AJ, et al. (2020) An engineered factor Va prevents bleeding induced by direct-acting oral anticoagulants by different mechanisms. Blood Advances. 4: 3716-3727
Mukherjee P, Lyden P, Fernández JA, et al. (2020) 3K3A-Activated Protein C Variant Does Not Interfere With the Plasma Clot Lysis Activity of Tenecteplase. Stroke. 51: 2236-2239
Kant R, Halder SK, Fernández JA, et al. (2020) Activated Protein C Attenuates Experimental Autoimmune Encephalomyelitis Progression by Enhancing Vascular Integrity and Suppressing Microglial Activation. Frontiers in Neuroscience. 14: 333
Calzavarini S, Prince Eladnani R, Saller F, et al. (2020) Platelet protein S limits venous but not arterial thrombosis propensity by controlling coagulation in the thrombus. Blood
Kondreddy V, Pendurthi UR, Xu X, et al. (2020) FVIIa (Factor VIIa) Induces Biased Cytoprotective Signal in Mice Through the Cleavage of PAR (Protease-Activated Receptor)-1 at Canonical Arg41 Site. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA120314244
Zilberman-Rudenko J, Deguchi H, Shukla M, et al. (2020) Cardiac Myosin Promotes Thrombin Generation and Coagulation In Vitro and In Vivo. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA120313990
Yamashita A, Zhang Y, Sanner MF, et al. (2020) C-terminal residues of activated protein C light chain contribute to its anticoagulant and cytoprotective activities. Journal of Thrombosis and Haemostasis : Jth
Heeb MJ, Fernández JA, Yamashita A, et al. (2019) Activated protein C anticoagulant activity is enhanced by skeletal muscle myosin. Haematologica
Deguchi H, Guo Z, Hayat M, et al. (2019) Molecular interaction site on procoagulant myosin for factor Xa-dependent prothrombin activation. The Journal of Biological Chemistry
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