Masahiro Sakagami, Ph.D.

Affiliations: 
2000 Virginia Commonwealth University, Richmond, VA, United States 
Area:
Pharmacy
Website:
https://app.pharmacy.vcu.edu/msakagam
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Parents

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Peter R. Byron grad student 2000 VCU
 (Kinetics and mechanisms of macromolecular disposition in the rat lung.)

Children

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Deepika Arora grad student 2008 VCU
Priya P. Nadkarni grad student 2009 VCU
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Publications

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Sakagami M. (2020) In vitro, ex vivo and in vivo methods of lung absorption for inhaled drugs. Advanced Drug Delivery Reviews
Raut A, Dhapare S, Venitz J, et al. (2019) Pharmacokinetic profile analyses for inhaled drugs in humans using the lung delivery and disposition model. Biopharmaceutics & Drug Disposition
Dhapare S, Sakagami M. (2018) Salvianolic acid B as an anti-emphysema agent I: In vitro stimulation of lung cell proliferation and migration, and protection against lung cell death, and in vivo lung STAT3 activation and VEGF elevation. Pulmonary Pharmacology & Therapeutics
Dhapare S, Li H, Sakagami M. (2018) Salvianolic acid B as an anti-emphysema agent II: In vivo reversal activities in two rat models of emphysema. Pulmonary Pharmacology & Therapeutics
Pouliot RA, Link PA, Mikhaiel NS, et al. (2016) Development and characterization of a naturally derived lung extracellular matrix hydrogel. Journal of Biomedical Materials Research. Part A
Nadkarni PP, Halquist MS, Karnes HT, et al. (2015) Pulmonary delivery of anorectic oxyntomodulin in rats: food intake suppression, reduced body weight gain and pharmacokinetics. Therapeutic Delivery. 6: 297-306
Gomez-Arroyo J, Sakagami M, Syed AA, et al. (2015) Iloprost reverses established fibrosis in experimental right ventricular failure. The European Respiratory Journal. 45: 449-62
Saluja B, Li H, Desai UR, et al. (2014) Sulfated caffeic acid dehydropolymer attenuates elastase and cigarette smoke extract-induced emphysema in rats: sustained activity and a need of pulmonary delivery. Lung. 192: 481-92
Sakagami M. (2013) Systemic delivery of biotherapeutics through the lung: opportunities and challenges for improved lung absorption. Therapeutic Delivery. 4: 1511-25
Saluja B, Thakkar JN, Li H, et al. (2013) Novel low molecular weight lignins as potential anti-emphysema agents: In vitro triple inhibitory activity against elastase, oxidation and inflammation. Pulmonary Pharmacology & Therapeutics. 26: 296-304
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