Rajani Korukonda, Ph.D.

Affiliations: 
2005 University of Tennessee Health Science Center, Memphis, TN, United States 
Area:
Pharmaceutical Chemistry
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Isaac Donkor grad student 2005 UTHSC
 (Exploration of calpain inhibitors incorporating constrained residues at P2 position and their potential as anti-tumor agents.)
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Publications

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Donkor IO, Korukonda R. (2008) Synthesis and calpain inhibitory activity of peptidomimetic compounds with constrained amino acids at the P2 position. Bioorganic & Medicinal Chemistry Letters. 18: 4806-8
Korukonda R, Guan N, Dalton JT, et al. (2006) Synthesis, calpain inhibitory activity, and cytotoxicity of P2-substituted proline and thiaproline peptidyl aldehydes and peptidyl alpha-ketoamides. Journal of Medicinal Chemistry. 49: 5282-90
Guan N, Korukonda R, Hurh E, et al. (2006) Apoptosis induced by novel aldehyde calpain inhibitors in human tumor cell lines. International Journal of Oncology. 29: 655-63
Donkor IO, Korukonda R, Huang TL, et al. (2003) Peptidyl aldehyde inhibitors of calpain incorporating P2-proline mimetics. Bioorganic & Medicinal Chemistry Letters. 13: 783-4
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