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Stephen M. Testa

Affiliations: 
University of Kentucky, Lexington, KY 
Area:
RNA Catalysts
Website:
http://www.chem.uky.edu/research/testa/
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"Stephen Testa"
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Parents

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Peter T. Gilham grad student 1994 Purdue
Douglas H. Turner post-doc 1995-1999 Rochester

Children

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Ashley K. Johnson grad student 2005 University of Kentucky
Dana A. Baum grad student 2001-2005 University of Kentucky
Perry P. Dotson grad student 2008 University of Kentucky
Jonathan L. Hart grad student 2012 University of Kentucky
Lalit Kumar grad student 2012 University of Kentucky

Collaborators

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John P. Selegue collaborator University of Kentucky
BETA: Related publications

Publications

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Testa SM, Selegue JP, French A, et al. (2018) Permanganate Oxidation of DNA Nucleotides: An Introductory Redox Laboratory Framed as a Murder Mystery Journal of Chemical Education. 95: 1840-1847
Thomas EM, Testa SM. (2016) The colorimetric determination of selectively cleaved adenosines and guanosines in DNA oligomers using bicinchoninic acid and copper. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry
Dotson PP, Hart J, Noe C, et al. (2012) Ribozyme-mediated trans insertion-splicing into target RNAs. Methods in Molecular Biology (Clifton, N.J.). 848: 385-94
Hart JL, Harris ZM, Testa SM. (2010) Analyzing and predicting the thermodynamic effects of the metabolite trehalose on nucleic acids. Biopolymers. 93: 1085-92
Dotson PP, Johnson AK, Testa SM. (2008) Tetrahymena thermophila and Candida albicans group I intron-derived ribozymes can catalyze the trans-excision-splicing reaction. Nucleic Acids Research. 36: 5281-9
Dotson PP, Frommeyer KN, Testa SM. (2008) Ribozyme mediated trans insertion-splicing of modified oligonucleotides into RNA. Archives of Biochemistry and Biophysics. 478: 81-4
Dotson PP, Sinha J, Testa SM. (2008) Kinetic characterization of the first step of the ribozyme-catalyzed trans excision-splicing reaction. The Febs Journal. 275: 3110-22
Dotson PP, Sinha J, Testa SM. (2008) A Pneumocystis carinii group I intron-derived ribozyme utilizes an endogenous guanosine as the first reaction step nucleophile in the trans excision-splicing reaction. Biochemistry. 47: 4780-7
Johnson AK, Sinha J, Testa SM. (2005) Trans insertion-splicing: ribozyme-catalyzed insertion of targeted sequences into RNAs. Biochemistry. 44: 10702-10
Alexander RC, Baum DA, Testa SM. (2005) 5' transcript replacement in vitro catalyzed by a group I intron-derived ribozyme. Biochemistry. 44: 7796-804
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