Bryan Knuckley
Affiliations: | Scripps Florida, Jupiter, FL, United States |
Area:
Protein arginine deiminase, bead based high throughput screen, serine hydrolaseGoogle:
"Bryan Knuckley"Mean distance: 39813
Parents
Sign in to add mentor| Paul R. Thompson | grad student | 2009 | University of South Carolina | |
| (Kinetic characterization of the protein arginine deiminase family: Mechanistic and inhibition studies.) | ||||
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Publications
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| DuBose MB, Sartawi T, Sawatzky TM, et al. (2022) A peptoid-based inhibitor of Protein Arginine Methyltransferase 1 (PRMT1) induces apoptosis and autophagy in cancer cells. The Journal of Biological Chemistry. 102205 |
| Mann SA, DeMart MK, May B, et al. (2020) Histone H4-based peptoids are inhibitors of Protein Arginine Methyltransferase 1 (PRMT1). The Biochemical Journal |
| Mann SA, Salsburg A, Causey CP, et al. (2019) The development and characterization of a chemical probe targeting PRMT1 over PRMT5. Bioorganic & Medicinal Chemistry. 27: 224-229 |
| Soares CA, Knuckley B. (2016) Mechanistic studies of the agmatine deiminase from Listeria monocytogenes. The Biochemical Journal. 473: 1553-61 |
| James ED, Knuckley B, Alqahtani N, et al. (2015) Two distinct cyclodipeptide synthases from a marine actinomycete catalyze biosynthesis of the same diketopiperazine natural product. Acs Synthetic Biology |
| Nguyen HC, Wang M, Salsburg A, et al. (2015) Development of a Plate-Based Screening Assay to Investigate the Substrate Specificity of the PRMT Family of Enzymes. Acs Combinatorial Science |
| Marchenko M, Thomson A, Ellis TN, et al. (2015) Development of a clickable activity-based protein profiling (ABPP) probe for agmatine deiminases. Bioorganic & Medicinal Chemistry. 23: 2159-67 |
| Thomson A, O'Connor S, Knuckley B, et al. (2014) Design, synthesis, and in vitro evaluation of an activity-based protein profiling (ABPP) probe targeting agmatine deiminases. Bioorganic & Medicinal Chemistry. 22: 4602-8 |
| Dreyton CJ, Knuckley B, Jones JE, et al. (2014) Mechanistic studies of protein arginine deiminase 2: evidence for a substrate-assisted mechanism. Biochemistry. 53: 4426-33 |
| Lewallen DM, Steckler CJ, Knuckley B, et al. (2012) Probing adenylation: Using a fluorescently labelled ATP probe to directly label and immunoprecipitate VopS substrates Molecular Biosystems. 8: 1701-1706 |