Bernard J. Komoroski, Ph.D.
Affiliations: | 2005 | University of Pittsburgh, Pittsburgh, PA, United States |
Area:
Pharmaceutical Chemistry, Pharmacology, PharmacyGoogle:
"Bernard Komoroski"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Raman Venkataramanan | grad student | 2005 | University of Pittsburgh | |
| (The direct and indirect effects of herbal products on common drug metabolizing enzymes and drug transporters.) | ||||
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Publications
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| Patel CG, Kornhauser D, Vachharajani N, et al. (2011) Saxagliptin, a potent, selective inhibitor of DPP-4, does not alter the pharmacokinetics of three oral antidiabetic drugs (metformin, glyburide or pioglitazone) in healthy subjects. Diabetes, Obesity & Metabolism. 13: 604-14 |
| Obermeier MT, Yao M, Khanna A, et al. (2010) In vitro characterization and pharmacokinetics of dapagliflozin (BMS-512148), a potent sodium-glucose cotransporter type II inhibitor, in animals and humans Drug Metabolism and Disposition. 38: 405-414 |
| Mirkov S, Komoroski BJ, Ramírez J, et al. (2007) Effects of green tea compounds on irinotecan metabolism. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 35: 228-33 |
| Venkataramanan R, Komoroski B, Strom S. (2006) In vitro and in vivo assessment of herb drug interactions. Life Sciences. 78: 2105-15 |
| Ramírez J, Komoroski BJ, Mirkov S, et al. (2006) Study of the genetic determinants of UGT1A1 inducibility by phenobarbital in cultured human hepatocytes. Pharmacogenetics and Genomics. 16: 79-86 |
| Komoroski BJ, Parise RA, Egorin MJ, et al. (2005) Effect of the St. John's wort constituent hyperforin on docetaxel metabolism by human hepatocyte cultures. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 6972-9 |
| RAMIREZ J, INNOCENTI F, KOMOROSKI B, et al. (2005) Genetic determinants of UGT1A1 inducibility Clinical Pharmacology & Therapeutics. 77: P25-P25 |
| Komoroski BJ, Zhang S, Cai H, et al. (2004) Induction and inhibition of cytochromes P450 by the St. John's wort constituent hyperforin in human hepatocyte cultures. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 32: 512-8 |
| Schuetz EG, Strom S, Yasuda K, et al. (2001) Disrupted bile acid homeostasis reveals an unexpected interaction among nuclear hormone receptors, transporters, and cytochrome P450. The Journal of Biological Chemistry. 276: 39411-8 |
| Venkataramanan R, Ramachandran V, Komoroski BJ, et al. (2000) Milk thistle, a herbal supplement, decreases the activity of CYP3A4 and uridine diphosphoglucuronosyl transferase in human hepatocyte cultures. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 28: 1270-3 |