Roman Osman, PhD

Affiliations: 
Icahn School of Medicine at Mount Sinai, New York, NY, United States 
Area:
Biophysics
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"Roman Osman"
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Publications

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Rodríguez Y, Gerona-Navarro G, Osman R, et al. (2019) In Silico Design and Molecular Basis for the Selectivity of Olinone Towards the First over the Second Bromodomain of BRD4. Proteins
Brown MC, Abdine A, Chavez J, et al. (2018) Unwinding of the Substrate Transmembrane Helix in Intramembrane Proteolysis. Biophysical Journal. 114: 1579-1589
Brown M, Abdine A, Chavez J, et al. (2016) Transmembrane Substrate Unfolding in Intramembrane Proteolysis Biophysical Journal. 110
Osman R, Mezei M, Engel S. (2015) The role of protein "Stability patches" in molecular recognition: A case study of the human growth hormone-receptor complex. Journal of Computational Chemistry
Maillet EL, Cui M, Jiang P, et al. (2015) Characterization of the Binding Site of Aspartame in the Human Sweet Taste Receptor. Chemical Senses. 40: 577-86
Osman R, Gomez JC, Mezei M, et al. (2015) Ligand-G Protein Allosteric Communication through Internal Waters in GPCR Complexes Biophysical Journal. 108: 3-3
Pasi M, Maddocks JH, Beveridge D, et al. (2014) μABC: a systematic microsecond molecular dynamics study of tetranucleotide sequence effects in B-DNA. Nucleic Acids Research. 42: 12272-83
Osman R, Mezei M, Barak D, et al. (2013) The Role of Internal Water in GPCR Complexes Biophysical Journal. 104
Joseph TT, Osman R. (2012) Convergent transmission of RNAi guide-target mismatch information across Argonaute internal allosteric network. Plos Computational Biology. 8: e1002693
Joseph TT, Osman R. (2012) Thermodynamic basis of selectivity in guide-target-mismatched RNA interference. Proteins. 80: 1283-98
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