Alan A. Pourpak, Ph.D.
Affiliations: | 2006 | University of Arizona, Tucson, AZ |
Area:
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Parents
Sign in to add mentor| Robert T. Dorr | grad student | 2006 | University of Arizona | |
| (Ethonafide-induced cytotoxicity is mediated by topoisomerase II inhibition in human prostate cancer cells.) | ||||
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| Meyers RO, Lambert JD, Hajicek N, et al. (2009) Synthesis, characterization, and anti-melanoma activity of tetra-O-substituted analogs of nordihydroguaiaretic acid. Bioorganic & Medicinal Chemistry Letters. 19: 4752-5 |
| Congdon LM, Pourpak A, Escalante AM, et al. (2008) Proteasomal inhibition stabilizes topoisomerase IIalpha protein and reverses resistance to the topoisomerase II poison ethonafide (AMP-53, 6-ethoxyazonafide). Biochemical Pharmacology. 75: 883-90 |
| Pourpak A, Landowski TH, Dorr RT. (2007) Ethonafide-induced cytotoxicity is mediated by topoisomerase II inhibition in prostate cancer cells. The Journal of Pharmacology and Experimental Therapeutics. 321: 1109-17 |
| Pourpak A, Dorr RT, Meyers RO, et al. (2007) Cytotoxic activity of Apomine is due to a novel membrane-mediated cytolytic mechanism independent of apoptosis in the A375 human melanoma cell line. Investigational New Drugs. 25: 107-14 |
| Pourpak A, Meyers RO, Samulitis BK, et al. (2006) Preclinical antitumor activity, pharmacokinetics and pharmacodynamics of imexon in mice. Anti-Cancer Drugs. 17: 1179-84 |