Pratap Singh, Ph.D.
Affiliations: | 2008 | Johns Hopkins University, Baltimore, MD |
Area:
Molecular Biology, General Biophysics, Cell BiologyGoogle:
"Pratap Singh"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| John T. Isaacs | grad student | 2008 | Johns Hopkins | |
| (Novel therapeutic agents for prostate cancer treatment: Design of bulky anti-androgens, thapsigargin analogs and inhibitors for prostate specific antigen.) | ||||
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Publications
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| Parng C, Singh P, Pittman DD, et al. (2018) Title: Translational PK/PD characterization and TMDD modeling of an anti-TFPI antibody, PF-06741086. Journal of Pharmaceutical Sciences |
| Chudasama VL, Zutshi A, Singh P, et al. (2015) Simulations of site-specific target-mediated pharmacokinetic models for guiding the development of bispecific antibodies. Journal of Pharmacokinetics and Pharmacodynamics. 42: 1-18 |
| Vugmeyster Y, Rohde C, Perreault M, et al. (2013) Agonistic TAM-163 antibody targeting tyrosine kinase receptor-B: Applying mechanistic modeling to enable preclinical to clinical translation and guide clinical trial design Mabs. 5: 373-383 |
| Singh P, LeBeau AM, Lilja H, et al. (2009) Molecular insights into substrate specificity of prostate specific antigen through structural modeling. Proteins. 77: 984-93 |
| LeBeau AM, Singh P, Isaacs JT, et al. (2009) Prostate-specific antigen is a "chymotrypsin-like" serine protease with unique P1 substrate specificity. Biochemistry. 48: 3490-6 |
| Singh P, Hallur G, Anchoori RK, et al. (2008) Rational design of novel antiandrogens for neutralizing androgen receptor function in hormone refractory prostate cancer. The Prostate. 68: 1570-81 |
| LeBeau AM, Singh P, Isaacs JT, et al. (2008) Potent and selective peptidyl boronic acid inhibitors of the serine protease prostate-specific antigen. Chemistry & Biology. 15: 665-74 |
| Singh P, Williams SA, Shah MH, et al. (2008) Mechanistic insights into the inhibition of prostate specific antigen by beta-lactam class compounds. Proteins. 70: 1416-28 |
| Goyal NK, Kumar A, Acharya RL, et al. (2007) Prediction of biochemical failure in localized carcinoma of prostate after radical prostatectomy by neuro-fuzzy. Indian Journal of Urology : Iju : Journal of the Urological Society of India. 23: 14-7 |
| Urushibara M, Ishioka J, Hyochi N, et al. (2007) Effects of steroidal and non-steroidal antiandrogens on wild-type and mutant androgen receptors. The Prostate. 67: 799-807 |