Leonard Irving Wiebe
Affiliations: | 1970-2003 | Pharmacy | University of Alberta, Edmonton, Alberta, Canada |
Area:
Pharmaceutical Chemistry, PharmacologyGoogle:
"Leonard Irving Wiebe"Bio:
http://www.worldcat.org/oclc/221234086
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Children
Sign in to add traineeKeykavous Parang | grad student | 1997 | University of Alberta |
Ebrahim Naimi | grad student | 2003 | University of Alberta |
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Publications
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Elsaidi HR, Yang XH, Ahmadi F, et al. (2019) Putative electron-affinic radiosensitizers and markers of hypoxic tissue: Synthesis and preliminary in vitro biological characterization of C3-amino-substituted benzotriazine dioxides (BTDOs). European Journal of Medicinal Chemistry. 165: 216-224 |
Sun W, Falzon C, Naimi E, et al. (2018) Synthesis of [18F]FAZA using Nosyl and Iodo Precursors for Nucleophilic Radiofluorination. Current Radiopharmaceuticals |
Kumar P, Roselt P, Reischl G, et al. (2017) β-[18F]Fluoro Azomycin Arabinoside (β-[18F]FAZA): Synthesis, radiofluorination and preliminary PET imaging of murine A431 tumors. Current Radiopharmaceuticals |
Kumar P, Bacchu V, Wiebe LI. (2015) The chemistry and radiochemistry of hypoxia-specific, radiohalogenated nitroaromatic imaging probes. Seminars in Nuclear Medicine. 45: 122-35 |
Mazzuca D, Angelov C, Wiebe LI. (2015) Synthesis of dialkylaminoaryl phosphonate bioisosteres of tyrosine and tyramine: a novel application of allene phosphonate chemistry for the synthesis of false substrates of tyrosinase - Journal of Applied Pharmaceutical Science. 5: 1-9 |
Xia Z, Knaus EE, Wiebe LI. (2013) Pharmacokinetics of 3'-O-retinoyl-5-fluoro-2'-deoxyuridine (RFUdR), a dual acting mutually masking prodrug, and its metabolites in tumor bearing mice. Current Drug Delivery. 10: 557-63 |
Mercer JR, McEwan AJ, Wiebe LI. (2013) [131I]IAZA as a molecular radiotherapeutic (MRT) drug: wash-out with cold IAZA accelerates clearance in a murine tumor model. Current Radiopharmaceuticals. 6: 87-91 |
Wuest M, Kumar P, Wang M, et al. (2012) In vitro and in vivo evaluation of [(18)F]F-GAZ, a novel oxygen-mimetic azomycin-glucose conjugate, for imaging hypoxic tumor. Cancer Biotherapy & Radiopharmaceuticals. 27: 473-80 |
Kumar P, Shustov G, Liang H, et al. (2012) Design, synthesis, and preliminary biological evaluation of 6-O-glucose-azomycin adducts for diagnosis and therapy of hypoxic tumors. Journal of Medicinal Chemistry. 55: 6033-46 |
Wiebe LI, Sun W, Zhou A, et al. (2012) Biochemistry and biology of 2'-Fluoro-2'-deoxythymidine (FT), a putative highly selective substrate for thymidine kinase type 2 (TK2). Current Radiopharmaceuticals. 5: 38-46 |