David A. Ostrov
Affiliations: | University of Florida, Gainesville, Gainesville, FL, United States |
Area:
Biochemistry, Molecular BiologyGoogle:
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Publications
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| Zhang X, Santos R, Debevec G, et al. (2020) Identification of small molecules by screening a mixture-based scaffold compound library for treatment of alpha-1 antitrypsin deficiency. Biochemical and Biophysical Research Communications. 527: 317-323 |
| Brown M, Zhang W, Yan D, et al. (2020) The role of survivin in the progression of pancreatic ductal adenocarcinoma (PDAC) and a novel survivin-targeted therapeutic for PDAC. Plos One. 15: e0226917 |
| Pan RY, Chu MT, Wang CW, et al. (2019) Identification of drug-specific public TCR driving severe cutaneous adverse reactions. Nature Communications. 10: 3569 |
| Vijay V, Miller R, Vue GS, et al. (2019) Interleukin-8 blockade prevents activated endothelial cell mediated proliferation and chemoresistance of acute myeloid leukemia. Leukemia Research. 84: 106180 |
| Zhang X, Kien P, Li D, et al. (2019) Targeting the site encoded by SERPINA1*E342K for treating alpha-1 antitrypsin deficiency-associated liver diseases. Febs Letters |
| Schutte RJ, Zhang X, An N, et al. (2019) Molecular docking predictions of fragrance binding to HLA molecules. Contact Dermatitis |
| Graham WV, He W, Marchiando AM, et al. (2019) Intracellular MLCK1 diversion reverses barrier loss to restore mucosal homeostasis. Nature Medicine |
| Ratnayake WS, Apostolatos CA, Apostolatos AH, et al. (2018) Oncogenic PKC-ι activates Vimentin during epithelial-mesenchymal transition in melanoma; a study based on PKC-ι and PKC-ζ specific inhibitors. Cell Adhesion & Migration. 1-17 |
| Ostrov DA, Alkanani A, McDaniel KA, et al. (2018) Methyldopa blocks MHC class II binding to disease-specific antigens in autoimmune diabetes. The Journal of Clinical Investigation |
| Ratnayake WS, Apostolatos AH, Ostrov DA, et al. (2017) Two novel atypical PKC inhibitors; ACPD and DNDA effectively mitigate cell proliferation and epithelial to mesenchymal transition of metastatic melanoma while inducing apoptosis. International Journal of Oncology |