David A. Boothman
Affiliations: | Case Western Reserve University, Cleveland Heights, OH, United States |
Area:
Biochemistry, Cell BiologyGoogle:
"David Boothman"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Sheldon Greer | grad student | University of Miami | |
| Arthur B. Pardee | grad student | Harvard Medical School |
Children
Sign in to add trainee| Kathryn E. Reinicke | grad student | 2007 | Case Western |
| Melissa C Srougi | grad student | 2001-2007 | Case Western (Cell Biology Tree) |
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Publications
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| Shukla K, Singh N, Lewis JE, et al. (2020) MTHFD2 Blockade Enhances the Efficacy of β-Lapachone Chemotherapy With Ionizing Radiation in Head and Neck Squamous Cell Cancer. Frontiers in Oncology. 10: 536377 |
| Starcher CL, Pay SL, Singh N, et al. (2020) Targeting Base Excision Repair in Cancer: NQO1-Bioactivatable Drugs Improve Tumor Selectivity and Reduce Treatment Toxicity Through Radiosensitization of Human Cancer. Frontiers in Oncology. 10: 1575 |
| Torrente L, Prieto-Farigua N, Falzone A, et al. (2020) Inhibition of TXNRD or SOD1 overcomes NRF2-mediated resistance to β-lapachone. Redox Biology. 30: 101440 |
| Hashemi-Sadraei N, Adra N, Kessler KA, et al. (2020) NAD(P)H: Quinone oxidoreductase (NQO1) and catalase expression in nonseminomatous germ cell tumors. Journal of Clinical Oncology. 38: 413-413 |
| Li X, Liu Z, Zhang A, et al. (2019) NQO1 targeting prodrug triggers innate sensing to overcome checkpoint blockade resistance. Nature Communications. 10: 3251 |
| Motea EA, Huang X, Singh N, et al. (2019) NQO1-dependent, tumor-selective radiosensitization of non-small cell lung cancers. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research |
| Gerber DE, Beg MS, Fattah F, et al. (2018) Phase 1 study of ARQ 761, a β-lapachone analogue that promotes NQO1-mediated programmed cancer cell necrosis. British Journal of Cancer |
| Motea EA, Fattah FJ, Xiao L, et al. (2018) Kub5-Hera RPRD1B deficiency promotes "BRCAness" and vulnerability to PARP inhibition in BRCA-proficient Breast Cancers. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research |
| Kahanda D, Singh N, Boothman DA, et al. (2018) Following anticancer drug activity in cell lysates with DNA devices. Biosensors & Bioelectronics. 119: 1-9 |
| Lewis J, Furdui C, Boothman D, et al. (2018) Genome-scale metabolic modeling identifies novel targets of redox metabolism in radiation-resistant tumors Free Radical Biology and Medicine. 128: S88 |