J. David Castle, Ph.D.
Affiliations: | Cell Biology | University of Virginia, Charlottesville, VA |
Area:
Cell Biology, Membrane Trafficking, Cholesterol RegulationWebsite:
https://med.virginia.edu/faculty/faculty-listing/jdc4r/Google:
"J. David Castle"Bio:
B.A. Carleton College 1968; Ph.D. in Cell Biology, Rockefeller University, 1974;
Postdoctoral with Wayne L. Hubbell, Biophysical Chemistry, Univ. California, Berkeley, 1975-78. Currently Professor of Cell Biology, University of Virginia School of Medicine.
Mean distance: 8.83 | S | N | B | C | P |
Parents
Sign in to add mentorGeorge E. Palade | grad student | 1974 | Rockefeller | |
(Studies on the secretory process of the rabbit parotid) | ||||
Wayne Lester Hubbell | post-doc | 1975-1978 | UC Berkeley |
Children
Sign in to add traineePeter R. Arvan | grad student | 1984 | Yale |
Mark von Zastrow | grad student | 1982-1987 | Yale (Neurotree) |
Haini Liao | grad student | 2007 | UVA |
Quyen L. Aoh | grad student | 2009 | UVA |
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Publications
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Bergeron J, Castle JD. (2020) Kathryn Howell (1939-2020) "The Secretory Pathway was Imprinted in her Heart". Traffic (Copenhagen, Denmark). 21: 552-555 |
Kiessling V, Kreutzberger AJB, Liang B, et al. (2018) A molecular mechanism for calcium-mediated synaptotagmin-triggered exocytosis. Nature Structural & Molecular Biology. 25: 911-917 |
Harris MT, Hussain SS, Inouye CM, et al. (2018) Reinterpretation of the localization of the ATP binding cassette transporter ABCG1 in insulin-secreting cells and insights regarding its trafficking and function. Plos One. 13: e0198383 |
Hussain SS, Harris MT, Kreutzberger AJB, et al. (2018) Control of Insulin Granule Formation and Function by the ABC Transporters ABCG1 and ABCA1 and by Oxysterol Binding Protein OSBP. Molecular Biology of the Cell |
Kreutzberger AJB, Kiessling V, Liang B, et al. (2017) Asymmetric Phosphatidylethanolamine Distribution Controls Fusion Pore Lifetime and Probability. Biophysical Journal |
Kreutzberger AJB, Kiessling V, Liang B, et al. (2017) Reconstitution of calcium-mediated exocytosis of dense-core vesicles. Science Advances. 3: e1603208 |
Mota LJ, Ramsden AE, Liu M, et al. (2009) SCAMP3 is a component of the Salmonella-induced tubular network and reveals an interaction between bacterial effectors and post-Golgi trafficking. Cellular Microbiology. 11: 1236-53 |
Aoh QL, Castle AM, Hubbard CH, et al. (2009) SCAMP3 negatively regulates epidermal growth factor receptor degradation and promotes receptor recycling. Molecular Biology of the Cell. 20: 1816-32 |
Balasubramanian N, Scott DW, Castle JD, et al. (2007) Arf6 and microtubules in adhesion-dependent trafficking of lipid rafts. Nature Cell Biology. 9: 1381-91 |
Liao H, Keller SR, Castle JD. (2006) Insulin-regulated aminopeptidase marks an antigen-stimulated recycling compartment in mast cells. Traffic (Copenhagen, Denmark). 7: 155-67 |