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Laura C. Simone, Ph.D.

Affiliations: 
2011 University of Nebraska Medical Center, Omaha, NE, United States 
Area:
Immunology, Cell Biology, Molecular Biology, Oncology
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Joyce C. Solheim grad student 2011 University of Nebraska Medical Center
 (Molecular insights into major histocompatibility complex class I folding and assembly.)

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Publications

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Simone LC, Smith BL, Solheim JC. (2012) Impact of beta 2-microglobulin on tapasin expression and covalent association. Cellular Immunology. 279: 66-9
Simone LC, Tuli A, Simone PD, et al. (2012) Analysis of major histocompatibility complex class I folding: novel insights into intermediate forms. Tissue Antigens. 79: 249-62
Simone LC, Georgesen CJ, Simone PD, et al. (2012) Productive association between MHC class I and tapasin requires the tapasin transmembrane/cytosolic region and the tapasin C-terminal Ig-like domain. Molecular Immunology. 49: 628-39
Simone LC, Wang X, Tuli A, et al. (2010) Effect of a tapasin mutant on the assembly of the mouse MHC class I molecule H2-K(d). Immunology and Cell Biology. 88: 57-62
Wang X, Simone LC, Tuli A, et al. (2009) Comparative analysis of the impact of a free cysteine in tapasin on the maturation and surface expression of murine MHC class I allotypes. International Journal of Immunogenetics. 36: 183-7
Simone LC, Wang X, Solheim JC. (2009) A transmembrane tail: interaction of tapasin with TAP and the MHC class I molecule. Molecular Immunology. 46: 2147-50
Tuli A, Sharma M, Wang X, et al. (2009) Amyloid precursor-like protein 2 association with HLA class I molecules. Cancer Immunology, Immunotherapy : Cii. 58: 1419-31
Simone LC, Wang X, Tuli A, et al. (2009) Influence of the tapasin C terminus on the assembly of MHC class I allotypes. Immunogenetics. 61: 43-54
Lin X, Wang X, Capek HL, et al. (2009) Effect of invariant chain on major histocompatibility complex class I molecule expression and stability on human breast tumor cell lines. Cancer Immunology, Immunotherapy : Cii. 58: 729-36
Tuli A, Sharma M, Wang X, et al. (2009) Erratum to: Amyloid precursor-like protein 2 association with HLA class I molecules Cancer Immunology, Immunotherapy. 59: 339-339
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