Ralph J. Abi-Habib, Ph.D.

Affiliations: 
2005 Wake Forest University, Winston-Salem, NC, United States 
Area:
Oncology, Biochemistry, Molecular Biology
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"Ralph Abi-Habib"
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Arthur E. Frankel grad student 2005 Wake Forest
 (Tumor protease -activated fusion toxins: A novel approach for the specific targeting of tumors.)
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Publications

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El-Mais N, Fakhoury I, Al Haddad M, et al. (2021) Human Recombinant Arginase I [HuArgI(Co)-PEG5000]-Induced Arginine Depletion Inhibits Pancreatic Cancer Cell Migration and Invasion Through Autophagy. Pancreas. 50: 1187-1194
El-Chami D, Al Haddad M, Abi-Habib R, et al. (2021) Recombinant anthrax lethal toxin inhibits cell motility and invasion in breast cancer cells through the dysregulation of Rho GTPases. Oncology Letters. 21: 163
El-Mais N, Fakhoury I, Abdellatef S, et al. (2021) Human recombinant arginase I [HuArgI (Co)-PEG5000]-induced arginine depletion inhibits ovarian cancer cell adhesion and migration through autophagy-mediated inhibition of RhoA. Journal of Ovarian Research. 14: 13
Swayden M, Bekdash A, Fakhoury I, et al. (2020) Activation of autophagy following [HuArgI (Co)-PEG5000]-induced arginine deprivation mediates cell death in colon cancer cells. Human Cell
Al-Koussa H, El Mais N, Maalouf H, et al. (2020) Arginine deprivation: a potential therapeutic for cancer cell metastasis? A review. Cancer Cell International. 20: 150
Khalil N, Abi-Habib RJ. (2019) [HuArgI (co)-PEG5000]-induced arginine deprivation leads to autophagy dependent cell death in pancreatic cancer cells. Investigational New Drugs
Al-Koussa H, Al-Haddad M, Abi-Habib R, et al. (2019) Human Recombinant Arginase I [HuArgI (Co)-PEG5000]-Induced Arginine Depletion Inhibits Colorectal Cancer Cell Migration and Invasion. International Journal of Molecular Sciences. 20
Nasreddine G, El-Sibai M, Abi-Habib RJ. (2019) Cytotoxicity of [HuArgI (co)-PEG5000]-induced arginine deprivation to ovarian Cancer cells is autophagy dependent. Investigational New Drugs
Audi H, Azar DF, Mahjoub F, et al. (2018) Cytotoxicity modulation of ruthenium(II) tris-bathophenanthroline complexes with systematically varied charge Journal of Photochemistry and Photobiology a: Chemistry. 351: 59-68
Al-Dimassi S, Salloum G, Saykali B, et al. (2016) Targeting the MAP kinase pathway in astrocytoma cells using a recombinant anthrax lethal toxin as a way to inhibit cell motility and invasion. International Journal of Oncology
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