Isin Cakir, Ph.D.

Affiliations: 
2010 Brown University, Providence, RI 
Area:
Molecular Biology
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"Isin Cakir"
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Eduardo A. Nillni grad student 2010 Brown
 (Regulation of energy homeostasis by hypothalamic Sirtuin 1 and endoplasmic reticulum stress.)
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Publications

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Çakır I, Lining Pan P, Hadley CK, et al. (2022) Sulforaphane reduces obesity by reversing leptin resistance. Elife. 11
Çakır I, Hadley CK, Pan PL, et al. (2022) Histone deacetylase 6 inhibition restores leptin sensitivity and reduces obesity. Nature Metabolism
Yong Y, Cakir I, Lining Pan P, et al. (2021) Endogenous cannabinoids are required for MC4R-mediated control of energy homeostasis. Proceedings of the National Academy of Sciences of the United States of America. 118
Wang Q, Zhang P, Cakir I, et al. (2021) Deletion of the feeding-induced hepatokine TSK ameliorates the melanocortin obesity syndrome. Diabetes
Hadley C, Cakir I, Cone RD. (2020) SAT-604 The Role of the Focal Adhesion Kinase Family in Leptin Receptor Signaling Journal of the Endocrine Society. 4
Andreoli MF, Donato J, Cakir I, et al. (2019) Leptin resensitization: a reversion of leptin resistant states. The Journal of Endocrinology
Cakir I, Diaz Martinez M, Lining Pan P, et al. (2019) Leptin Receptor Signaling in Sim1-expressing Neurons Regulates Body Temperature and Adaptive Thermogenesis. Endocrinology
Cakir I, Nillni EA. (2019) Endoplasmic Reticulum Stress, the Hypothalamus, and Energy Balance. Trends in Endocrinology and Metabolism: Tem
Anderson EJP, Ghamari-Langroudi M, Cakir I, et al. (2018) Late onset obesity in mice with targeted deletion of potassium inward rectifier Kir7.1 from cells expressing the melanocortin-4 receptor. Journal of Neuroendocrinology. e12670
Litt MJ, Okoye GD, Lark D, et al. (2017) Loss of the melanocortin-4 receptor in mice causes dilated cardiomyopathy. Elife. 6
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