Jason Moffat, Ph.D.
Affiliations: | 2002 | University of Toronto, Toronto, ON, Canada |
Area:
Genetics, Molecular Biology, Cell BiologyGoogle:
"Jason Moffat"Mean distance: (not calculated yet)
Parents
Sign in to add mentorBrenda Andrews | grad student | 2002 | University of Toronto | |
(Functions for Pho85 cyclin -dependent protein kinases in Saccharomyces cerevisiae.) |
Children
Sign in to add traineeKim Blakely | grad student | 2012 | University of Toronto |
Sanna N Masud | research scientist | University of Toronto |
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Publications
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Lin P, Lourenco C, Cruickshank J, et al. (2023) Topoisomerase 1 Inhibition in MYC-Driven Cancer Promotes Aberrant R-Loop Accumulation to Induce Synthetic Lethality. Cancer Research. OF1-OF15 |
Varland S, Silva RD, Kjosås I, et al. (2023) N-terminal acetylation shields proteins from degradation and promotes age-dependent motility and longevity. Nature Communications. 14: 6774 |
Billmann M, Ward HN, Aregger M, et al. (2023) Reproducibility metrics for context-specific CRISPR screens. Cell Systems. 14: 418-422.e2 |
Bock C, Datlinger P, Chardon F, et al. (2022) High-content CRISPR screening. Nature Reviews. Methods Primers. 2 |
Chan K, Farias AG, Lee H, et al. (2022) Survival-based CRISPR genetic screens across a panel of permissive cell lines identify common and cell-specific SARS-CoV-2 host factors. Heliyon. e12744 |
Masud SN, Chandrashekhar M, Aregger M, et al. (2022) Author Correction: Chemical genomics with pyrvinium identifies C1orf115 as a regulator of drug efflux. Nature Chemical Biology |
Masud SN, Chandrashekhar M, Aregger M, et al. (2022) Chemical genomics with pyrvinium identifies C1orf115 as a regulator of drug efflux. Nature Chemical Biology |
Mair B, Aregger M, Tong AHY, et al. (2022) A Method to Map Gene Essentiality of Human Pluripotent Stem Cells by Genome-Scale CRISPR Screens with Inducible Cas9. Methods in Molecular Biology (Clifton, N.J.). 2377: 1-27 |
Rahman M, Billmann M, Costanzo M, et al. (2021) A method for benchmarking genetic screens reveals a predominant mitochondrial bias. Molecular Systems Biology. 17: e10013 |
Lawson KA, Sousa CM, Zhang X, et al. (2020) Functional genomic landscape of cancer-intrinsic evasion of killing by T cells. Nature |