Michael G. Malkowski
Affiliations: | Structural Biology | State University of New York, Buffalo, Buffalo, NY, United States |
Area:
Biochemistry, Bioinformatics Biology, General BiologyGoogle:
"Michael Malkowski"Mean distance: (not calculated yet)
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Publications
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| Dong L, Malkowski MG. (2023) Defining the Conformational Ensembles Associated with Ligand Binding to Cyclooxygenase-2. Biochemistry. 62: 3134-3144 |
| Dong L, Anderson A, Malkowski MG. (2019) Arg-513 and Leu-531 Are Key Residues Governing Time-Dependent Inhibition of Cyclooxygenase-2 by Aspirin and Celebrex. Biochemistry |
| Smith WL, Malkowski MG. (2019) Interactions of fatty acids, nonsteroidal anti-inflammatory drugs, and coxibs with the catalytic and allosteric subunits of cyclooxygenases-1 and -2. The Journal of Biological Chemistry. 294: 1697-1705 |
| Giménez-Bastida JA, Boeglin WE, Boutaud O, et al. (2018) Residual cyclooxygenase activity of aspirin-acetylated COX-2 forms 15 R-prostaglandins that inhibit platelet aggregation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201801018R |
| Dong L, Yuan C, Orlando BJ, et al. (2016) Fatty Acid Binding to the Allosteric Subunit of Cyclooxygenase-2 Relieves a Tonic Inhibition of the Catalytic Subunit. The Journal of Biological Chemistry |
| Orlando BJ, Malkowski MG. (2016) Crystal structure of rofecoxib bound to human cyclooxygenase-2. Acta Crystallographica. Section F, Structural Biology Communications. 72: 772-776 |
| Orlando BJ, Malkowski MG. (2016) Substrate Selective Inhibition of Cyclooxygenase-2 by Fenamic Acid Derivatives is Dependent on Peroxide Tone. The Journal of Biological Chemistry |
| Lucido MJ, Orlando BJ, Vecchio AJ, et al. (2016) Crystal Structure of Aspirin-Acetylated Human Cyclooxygenase-2: Insight into the Formation of Products with Reversed Stereochemistry. Biochemistry. 55: 1226-38 |
| Orlando BJ, Borbat PP, Georgieva ER, et al. (2015) Pulsed Dipolar Spectroscopy Reveals that Tyrosyl Radicals are generated in Both Monomers of the Cyclooxygenase-2 Dimer. Biochemistry |
| Otsuka T, Kirkham C, Brauer A, et al. (2015) The Vaccine Candidate, Substrate Binding Protein SBP2, Plays a Key Role in Arginine Uptake, which is Required for Growth of Moraxella catarrhalis. Infection and Immunity |