Thomas A. Munro, Ph.D.

Affiliations: 
2006 University of Melbourne (Australia) 
Area:
Organic Chemistry, Pharmacology
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"Thomas Munro"
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Mark Rizzacasa grad student 2006 University of Melbourne (Australia)
 (The Chemistry of Salvia divinorum.)
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Munro TA, Xu W, Ho DM, et al. (2013) Studies toward bivalent κ opioids derived from salvinorin A: heteromethylation of the furan ring reduces affinity. Beilstein Journal of Organic Chemistry. 9: 2916-24
Munro TA, Huang XP, Inglese C, et al. (2013) Selective κ opioid antagonists nor-BNI, GNTI and JDTic have low affinities for non-opioid receptors and transporters. Plos One. 8: e70701
Schmid CL, Streicher JM, Groer CE, et al. (2013) Functional selectivity of 6'-guanidinonaltrindole (6'-GNTI) at κ-opioid receptors in striatal neurons. The Journal of Biological Chemistry. 288: 22387-98
Munro TA, Ho DM, Cohen BM. (2012) Salvinorin B meth-oxy-methyl ether. Acta Crystallographica. Section E, Structure Reports Online. 68: o3225-6
Munro TA, Berry LM, Van't Veer A, et al. (2012) Long-acting κ opioid antagonists nor-BNI, GNTI and JDTic: pharmacokinetics in mice and lipophilicity. Bmc Pharmacology. 12: 5
Mendelson JE, Coyle JR, Lopez JC, et al. (2011) Lack of effect of sublingual salvinorin A, a naturally occurring kappa opioid, in humans: a placebo-controlled trial. Psychopharmacology. 214: 933-9
Béguin C, Duncan KK, Munro TA, et al. (2009) Modification of the furan ring of salvinorin A: identification of a selective partial agonist at the kappa opioid receptor. Bioorganic & Medicinal Chemistry. 17: 1370-80
Munro TA, Duncan KK, Xu W, et al. (2008) Standard protecting groups create potent and selective kappa opioids: salvinorin B alkoxymethyl ethers. Bioorganic & Medicinal Chemistry. 16: 1279-86
Béguin C, Potter DN, Dinieri JA, et al. (2008) N-methylacetamide analog of salvinorin A: a highly potent and selective kappa-opioid receptor agonist with oral efficacy. The Journal of Pharmacology and Experimental Therapeutics. 324: 188-95
Munro TA, Duncan KK, Staples RJ, et al. (2007) 8-epi-Salvinorin B: crystal structure and affinity at the kappa opioid receptor. Beilstein Journal of Organic Chemistry. 3: 1
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