Jacques R. Fresco

Affiliations: 
Princeton University, Princeton, NJ 
Area:
nucleic acid third-strand binding to Watson-Crick duplexes
Website:
http://molbio.princeton.edu/faculty/molbio-faculty/107-fresco
Google:
"Jacques Fresco"
Mean distance: 9.23
 
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Aaron Bendich grad student 1953 NYU
 (Biochemical studies on nucleic acids)
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Publications

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Gold MP, Fresco JR. (2017) A Role for the Mutagenic DNA Self-Catalyzed Depurination Mechanism in the Evolution of 7SL-Derived RNAs. Journal of Molecular Evolution
Fresco JR, Amosova O. (2017) Site-Specific Self-Catalyzed DNA Depurination: A Biological Mechanism That Leads to Mutations and Creates Sequence Diversity. Annual Review of Biochemistry. 86: 461-484
Amosova O, Alvarez-Dominguez JR, Fresco JR. (2015) Why the DNA self-depurination mechanism operates in HB-β but not in β-globin paralogs HB-δ, HB-ɛ1, HB-γ1 and HB-γ2. Mutation Research. 778: 11-17
Alvarez-Dominguez JR, Amosova O, Fresco JR. (2013) Self-catalytic DNA depurination underlies human β-globin gene mutations at codon 6 that cause anemias and thalassemias. The Journal of Biological Chemistry. 288: 11581-9
Amosova O, Smith A, Fresco JR. (2011) The consensus sequence for self-catalyzed site-specific G residue depurination in DNA. The Journal of Biological Chemistry. 286: 36316-21
Amosova O, Kumar V, Deutsch A, et al. (2011) Self-catalyzed site-specific depurination of G residues mediated by cruciform extrusion in closed circular DNA plasmids. The Journal of Biological Chemistry. 286: 36322-30
Varganov Y, Amosova O, Fresco JR. (2007) Third strand-mediated psoralen-induced correction of the sickle cell mutation on a plasmid transfected into COS-7 cells. Gene Therapy. 14: 173-9
Amosova O, Coulter R, Fresco JR. (2006) Self-catalyzed site-specific depurination of guanine residues within gene sequences. Proceedings of the National Academy of Sciences of the United States of America. 103: 4392-7
Liang H, Landweber LF, Fresco JR. (2005) Are stop codons recognized by base triplets in the large ribosomal RNA subunit? Rna (New York, N.Y.). 11: 1478-84
Dolinnaya NG, Fresco JR. (2003) Conformational polymorphism of d(A-G)n and related oligonucleotide sequences. Progress in Nucleic Acid Research and Molecular Biology. 75: 321-47
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