Adrian T. Keatinge-Clay
Affiliations: | Chemistry & Biochemistry | University of Texas at Austin, Austin, Texas, U.S.A. |
Area:
Natural Product BiochemistryWebsite:
http://www.cm.utexas.edu/adrian_keatinge-clayGoogle:
"Adrian Keatinge-Clay"Mean distance: 8.79 | S | N | B | C | P |
Parents
Sign in to add mentor| Robert M. Stroud | grad student | 2001-2004 | UCSF | |
| (Catalysis and specificity of aromatic polyketide synthases in the early stages of antibiotic synthesis.) | ||||
Children
Sign in to add trainee| Clinton Albert Taylor IV | research assistant | 2008-2010 | (Neurotree) |
| Constance B. Bailey | grad student | 2015 | UT Austin |
| David Cole Stevens | post-doc |
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Publications
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| Dickinson MS, Miyazawa T, McCool RS, et al. (2022) Priming enzymes from the pikromycin synthase reveal how assembly-line ketosynthases catalyze carbon-carbon chemistry. Structure (London, England : 1993) |
| Hirsch M, Fitzgerald BJ, Keatinge-Clay AT. (2021) How -Acyltransferase Assembly-Line Ketosynthases Gatekeep for Processed Polyketide Intermediates. Acs Chemical Biology. 16: 2515-2526 |
| Miyazawa T, Hirsch M, Zhang Z, et al. (2020) An in vitro platform for engineering and harnessing modular polyketide synthases. Nature Communications. 11: 80 |
| Zhang Z, Cepeda AJ, Robles ML, et al. (2019) General chemoenzymatic route to two-stereocenter triketides employing assembly line ketoreductases. Chemical Communications (Cambridge, England) |
| Meinke JL, Simon AJ, Wagner DT, et al. (2019) Employing 25-Residue Docking Motifs from Modular Polyketide Synthases as Orthogonal Protein Connectors. Acs Synthetic Biology |
| Valencia LE, Zhang Z, Cepeda AJ, et al. (2019) Seven-enzyme in vitro cascade to (3R)-3-hydroxybutyryl-CoA. Organic & Biomolecular Chemistry |
| Meinke JL, Mehaffey MR, Wagner DT, et al. (2018) Structural and Functional Studies of a gem-Dimethylating Methyltransferase from a trans-Acyltransferase Assembly Line. Acs Chemical Biology |
| Liu C, Yuan M, Xu X, et al. (2018) Substrate-bound Structures of a Ketoreductase from Amphotericin Modular Polyketide Synthase. Journal of Structural Biology |
| Vander Wood DA, Keatinge-Clay AT. (2018) The Modules of trans-Acyltransferase Assembly Lines Redefined with a Central Acyl Carrier Protein. Proteins |
| Wagner DT, Zhang Z, Meoded RA, et al. (2018) Structural and Functional Studies of a Pyran Synthase Domain from a trans-Acyltransferase Assembly Line. Acs Chemical Biology |