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Steven M. Sine

Affiliations: 
Mayo Clinic College of Medicine, Rochester, MN, United States 
Area:
Receptor Biology
Website:
http://mayoresearch.mayo.edu/receptor_biology/index.cfm
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"Steven Sine"
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Parents

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Palmer W. Taylor grad student 1980 UCSD
 (The relationship between ligand binding and functional state of the acetylcholine receptor)
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Publications

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Mazzaferro S, Kang G, Natarajan K, et al. (2024) Structural bases for stoichiometry-selective calcium potentiation of a neuronal nicotinic receptor. British Journal of Pharmacology
Burke SM, Avstrikova M, Noviello CM, et al. (2024) Structural mechanisms of α7 nicotinic receptor allosteric modulation and activation. Cell. 187: 1160-1176.e21
Mazzaferro S, Msekela DJ, Cooper EC, et al. (2022) Genetic Variant in Nicotinic Receptor α4-Subunit Causes Sleep-Related Hyperkinetic Epilepsy via Increased Channel Opening. International Journal of Molecular Sciences. 23
Mazzaferro S, Strikwerda JR, Sine SM. (2021) Stoichiometry-selective modulation of α4β2 nicotinic acetylcholine receptors by divalent cations. British Journal of Pharmacology
Strikwerda JR, Sine SM. (2021) Unmasking coupling between channel gating and ion permeation in the muscle nicotinic receptor. Elife. 10
Noviello CM, Gharpure A, Mukhtasimova N, et al. (2021) Structure and gating mechanism of the α7 nicotinic acetylcholine receptor. Cell
Natarajan K, Mukhtasimova N, Corradi J, et al. (2020) Mechanism of calcium potentiation of the α7 nicotinic acetylcholine receptor. The Journal of General Physiology. 152
Mazzaferro S, Whiteman ST, Alcaino C, et al. (2020) NACHO and 14-3-3 promote expression of distinct subunit stoichiometries of the α4β2 acetylcholine receptor. Cellular and Molecular Life Sciences : Cmls
Shen XM, Di L, Shen S, et al. (2020) A novel fast-channel myasthenia caused by mutation in β subunit of AChR reveals subunit-specific contribution of the intracellular M1-M2 linker to channel gating. Experimental Neurology. 113375
Shen XM, Milone M, Wang HL, et al. (2019) Slow-channel myasthenia due to novel mutation in M2 domain of AChR delta subunit. Annals of Clinical and Translational Neurology
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