Shan Zha, Ph.D.
Affiliations: | 1998-2004 | Pharmacology and Molecular Sciences | Johns Hopkins University, Baltimore, MD |
2004-2009 | Molecular Genetics | Harvard - Boston Children's Hospital | |
2009- | Institute for Cancer Genetics | Columbia University College of Physicians and Surgeons, New York, NY, United States |
Area:
DNA repair, Oncology, Molecular Biology, PharmacologyGoogle:
"Shan Zha"Mean distance: (not calculated yet)
Parents
Sign in to add mentorWilliam B. Isaacs | grad student | 1998-2004 | Johns Hopkins | |
(Cyclooxygenase-2 and alpha-methylacyl-CoA racemase in prostate cancer.) | ||||
Frederick W. Alt | post-doc | 2004-2009 | Harvard - Boston Children's Hospital |
Children
Sign in to add traineeKenta Yamamoto | grad student | 2010-2015 | Columbia University Medical School |
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Publications
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Wu-Baer F, Wong M, Tschoe L, et al. (2023) ATM/ATR Phosphorylation of CtIP on Its Conserved Sae2-like Domain Is Required for Genotoxin-Induced DNA Resection but Dispensable for Animal Development. Cells. 12 |
Li Z, Duan S, Hua X, et al. (2023) Asymmetric distribution of parental H3K9me3 in S phase silences L1 elements. Nature. 623: 643-651 |
Cimprich KA, Li GM, Demaria S, et al. (2023) The crosstalk between DNA repair and immune responses. Molecular Cell. 83: 3582-3587 |
Shao Z, Lee BJ, Zhang H, et al. (2023) Inactive PARP1 causes embryonic lethality and genome instability in a dominant-negative manner. Proceedings of the National Academy of Sciences of the United States of America. 120: e2301972120 |
Menolfi D, Lee BJ, Zhang H, et al. (2023) ATR kinase supports normal proliferation in the early S phase by preventing replication resource exhaustion. Nature Communications. 14: 3618 |
Schvartzman JM, Forsyth G, Walch H, et al. (2023) Oncogenic IDH mutations increase heterochromatin-related replication stress without impacting homologous recombination. Molecular Cell |
Zhu Y, Jiang W, Lee BJ, et al. (2023) Phosphorylation of DNA-PKcs at the S2056 cluster ensures efficient and productive lymphocyte development in XLF-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. 120: e2221894120 |
Menolfi D, Lee BJ, Zhang H, et al. (2023) ATR kinase supports normal proliferation in the early S phase by preventing replication resource exhaustion. Biorxiv : the Preprint Server For Biology |
Zagelbaum J, Schooley A, Zhao J, et al. (2023) Author Correction: Multiscale reorganization of the genome following DNA damage facilitates chromosome translocations via nuclear actin polymerization. Nature Structural & Molecular Biology |
Langelier MF, Lin X, Zha S, et al. (2023) Clinical PARP inhibitors allosterically induce PARP2 retention on DNA. Science Advances. 9: eadf7175 |