Alfredo J. Hernandez, Ph.D.

Affiliations: 
2010 Texas A & M University, College Station, TX, United States 
Area:
Biochemistry, Molecular Biology
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Jorge Cruz-Reyes grad student 2010 Texas A & M
 (RNA editing in trypanosomes: Substrate recognition and its integration to RNA metabolism.)
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Publications

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Hernandez AJ, Lee SJ, Thompson NJ, et al. (2022) Residues located in the primase domain of the bacteriophage T7 primase-helicase are essential for loading the hexameric complex onto DNA. The Journal of Biological Chemistry. 101996
Hernandez AJ, Lee SJ, Chang S, et al. (2020) Catalytically inactive T7 DNA polymerase imposes a lethal replication roadblock. The Journal of Biological Chemistry
Hernandez AJ, Zovoilis A, Cifuentes-Rojas C, et al. (2019) B2 and ALU retrotransposons are self-cleaving ribozymes whose activity is enhanced by EZH2. Proceedings of the National Academy of Sciences of the United States of America
Hernandez AJ, Richardson CC. (2018) Gp2.5, the Multifunctional Bacteriophage T7 Single-stranded DNA Binding Protein. Seminars in Cell & Developmental Biology
Ilic S, Akabayov SR, Froimovici R, et al. (2017) Modulation of RNA primer formation by Mn(II)-substituted T7 DNA primase. Scientific Reports. 7: 5797
Hernandez AJ, Richardson CC. (2017) Kinetics of Lagging-strand DNA Synthesis In Vitro by the Bacteriophage T7 Replication Proteins. Journal of Visualized Experiments : Jove
Zhu B, Wang L, Mitsunobu H, et al. (2017) Deep-sea vent phage DNA polymerase specifically initiates DNA synthesis in the absence of primers. Proceedings of the National Academy of Sciences of the United States of America
Zovoilis A, Cifuentes-Rojas C, Chu HP, et al. (2016) Destabilization of B2 RNA by EZH2 Activates the Stress Response. Cell. 167: 1788-1802.e13
Hernandez AJ, Lee SJ, Richardson CC. (2016) Primer release is the rate-limiting event in lagging-strand synthesis mediated by the T7 replisome. Proceedings of the National Academy of Sciences of the United States of America
Zhu B, Hernandez A, Tan M, et al. (2015) Synthesis of 2'-Fluoro RNA by Syn5 RNA polymerase. Nucleic Acids Research
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