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Donna M. Huryn

Affiliations: 
Pharmacy University of Pittsburgh, Pittsburgh, PA, United States 
Area:
Drug Discovery and Medicinal Chemistry
Website:
http://webdev.chem.upenn.edu/chem/research/faculty.php?id=22
Google:
"Donna Huryn"
Bio:

https://list.pitt.edu/pipermail/pharmsciencesfac/attachments/20100910/dfb686e8/dmhuryncv090310.pdf

Mean distance: 8.15
 
SNBCP

Parents

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Amos B. Smith, III grad student 1986 Penn
 (A unified synthetic strategy towards the construction of a family of fungal metabolities : the synthesis of (+)-mycorrhizin a and (-)-gilmicolin; studies towards the synthesis of (+)-mikrolin)
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Publications

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Cotticelli MG, Forestieri R, Xia S, et al. (2020) Identification of a Novel Oleic Acid Analog with Protective Effects in Multiple Cellular Models of Friedreich Ataxia. Acs Chemical Neuroscience
Loro E, Sengupta K, Bogdanovich S, et al. (2020) High-throughput identification of post-transcriptional utrophin up-regulators for Duchenne muscle dystrophy (DMD) therapy. Scientific Reports. 10: 2132
Long K, Kostman SJ, Fernandez C, et al. (2019) Do Zebrafish Obey Lipinski Rules? Acs Medicinal Chemistry Letters. 10: 1002-1006
LaPorte MG, Burnett JC, Colombo R, et al. (2018) Optimization of Phenyl Indole Inhibitors of the AAA+ ATPase p97. Acs Medicinal Chemistry Letters. 9: 1075-1081
LaPorte MG, Wang Z, Colombo R, et al. (2016) Optimization of pyrazole-containing 1,2,4-triazolo-[3,4-b]thiadiazines, a new class of STAT3 pathway inhibitors. Bioorganic & Medicinal Chemistry Letters
Johnston PA, Nguyen MM, Dar JA, et al. (2016) Development and Implementation of a High-Throughput High-Content Screening Assay to Identify Inhibitors of Androgen Receptor Nuclear Localization in Castration-Resistant Prostate Cancer Cells. Assay and Drug Development Technologies. 14: 226-39
Alverez C, Bulfer SL, Chakrasali R, et al. (2016) Allosteric Indole Amide Inhibitors of p97: Identification of a Novel Probe of the Ubiquitin Pathway. Acs Medicinal Chemistry Letters. 7: 182-7
Lassalas P, Gay B, Lasfargeas C, et al. (2016) Structure Property Relationships of Carboxylic Acid Isosteres. Journal of Medicinal Chemistry
Alverez C, Arkin MR, Bulfer SL, et al. (2015) Structure-Activity Study of Bioisosteric Trifluoromethyl and Pentafluorosulfanyl Indole Inhibitors of the AAA ATPase p97. Acs Medicinal Chemistry Letters. 6: 1225-30
Johnston PA, Sen M, Hua Y, et al. (2015) HCS Campaign to Identify Selective Inhibitors of IL-6-Induced STAT3 Pathway Activation in Head and Neck Cancer Cell Lines. Assay and Drug Development Technologies. 13: 356-76
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