Melinda E. Varney, Ph.D.

Affiliations: 
2010 Biomedical Sciences Marshall University, Huntington, WV, United States 
Area:
Cell Biology, Genetics
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"Melinda Varney"
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Vincent E. Sollars grad student 2010 Marshall University
 (Genetic and environmental factors suggest that dietary fatty acid content, lipid metabolism, and bone properties are key regulators of myeloid progenitor cell frequency.)
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Publications

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Niederkorn M, Hueneman K, Choi K, et al. (2020) TIFAB Regulates USP15-Mediated p53 Signaling during Stressed and Malignant Hematopoiesis. Cell Reports. 30: 2776-2790.e6
Varney ME, Boehm DT, DeRoos K, et al. (2018) Whole Cell Immunization, Unlike Acellular Immunization, Mimics Naïve Infection by Driving Hematopoietic Stem and Progenitor Cell Expansion in Mice. Frontiers in Immunology. 9: 2376
Niederkorn M, Varney M, Smith MA, et al. (2016) Tifab, a Del(5q) MDS/AML Gene, Regulates USP15 Activity and p53 Blood. 128: 1130-1130
Varney ME, Niederkorn M, Konno H, et al. (2015) Loss of Tifab, a del(5q) MDS gene, alters hematopoiesis through derepression of Toll-like receptor-TRAF6 signaling. The Journal of Experimental Medicine. 212: 1967-85
Varney ME, Melgar K, Niederkorn M, et al. (2015) Deconstructing innate immune signaling in Myelodysplastic Syndromes. Experimental Hematology
Guo F, Zhang S, Grogg M, et al. (2013) Mouse gene targeting reveals an essential role of mTOR in hematopoietic stem cell engraftment and hematopoiesis. Haematologica. 98: 1353-8
Fang J, Rhyasen G, Bolanos L, et al. (2012) Cytotoxic effects of bortezomib in myelodysplastic syndrome/acute myeloid leukemia depend on autophagy-mediated lysosomal degradation of TRAF6 and repression of PSMA1. Blood. 120: 858-67
Varney M, Jerez A, Fang J, et al. (2012) Tifab, a Novel Candidate Gene in Deletion Chromosome 5q, Contributes to Deregulation of NF-κB Signaling in MDS/AML. Blood. 120: 2812-2812
Varney ME, Buchanan JT, Dementieva Y, et al. (2011) A high omega-3 fatty acid diet has different effects on early and late stage myeloid progenitors. Lipids. 46: 47-57
Fan J, Eastham L, Varney ME, et al. (2010) Silencing and re-expression of retinoic acid receptor beta2 in human melanoma. Pigment Cell & Melanoma Research. 23: 419-29
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