John W. Kappler
Affiliations: | University of Colorado Anschutz Medical Campus, Denver, Aurora, CO |
Area:
Biochemistry, ImmunologyWebsite:
https://www.nationaljewish.org/doctors-departments/providers/researchers/john-w-kapplerGoogle:
"John Wayne Kappler" OR "John W. Kappler"Bio:
https://medschool.cuanschutz.edu/barbara-davis-center-for-diabetes/about/faculty/john-kappler
https://www.proquest.com/openview/0b061dc87fb8769a85ed7f9283daabc2/1
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Parents
Sign in to add mentor| Gordon H. Sato | grad student | 1969 | Brandeis (Neurotree) | |
| (DNA methylation in eukaryotic cells) | ||||
Children
Sign in to add trainee| Linh K. Lu | grad student | 2001 | University of Colorado, Denver |
| Kira Rubtsova | grad student | 2009 | University of Colorado, Denver |
| Brian D. Stadinski | grad student | 2009 | University of Colorado, Denver |
| Bernard C. Collins | grad student | 2011 | University of Colorado, Denver |
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Publications
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| Ramos SA, Morton JJ, Yadav P, et al. (2021) Generation of functional human thymic cells from induced pluripotent stem cells. The Journal of Allergy and Clinical Immunology |
| Reed BK, Kappler JW. (2021) Hidden in Plain View: Discovery of Chimeric Diabetogenic CD4 T Cell Neo-Epitopes. Frontiers in Immunology. 12: 669986 |
| Falta MT, Crawford JC, Tinega AN, et al. (2021) Beryllium-specific CD4+ T cells induced by chemokine neoantigens perpetuate inflammation. The Journal of Clinical Investigation |
| Reed B, Crawford F, Hill RC, et al. (2021) Lysosomal cathepsin creates chimeric epitopes for diabetogenic CD4 T cells via transpeptidation. The Journal of Experimental Medicine. 218 |
| Cepeda JR, Sekhar NS, Han J, et al. (2020) A monoclonal antibody with broad specificity for the ligands of insulin B:9-23 reactive T cells prevents spontaneous type 1 diabetes in mice. Mabs. 12: 1836714 |
| Gray JI, Al-Khabouri S, Morton F, et al. (2020) Tolerance induction in memory CD4 T cells is partial and reversible. Immunology |
| Phalke S, Aviszus K, Rubtsova K, et al. (2020) Age Associated B Cells Appear in Patients with Granulomatous Lung Diseases. American Journal of Respiratory and Critical Care Medicine |
| Krovi SH, Kappler JW, Marrack P, et al. (2019) Inherent reactivity of unselected TCR repertoires to peptide-MHC molecules. Proceedings of the National Academy of Sciences of the United States of America |
| Wang Y, Sosinowski T, Novikov A, et al. (2019) How C-terminal additions to insulin B-chain fragments create superagonists for T cells in mouse and human type 1 diabetes. Science Immunology. 4 |
| Williams T, Krovi H, Landry LG, et al. (2018) Development of T cell lines sensitive to antigen stimulation. Journal of Immunological Methods |