Herman O. Sintim, DPhil
Affiliations: | Chemistry and Biochemistry | University of Maryland, College Park, College Park, MD |
Area:
Chemical Biology, OrganicWebsite:
http://www.chem.umd.edu/research/facultyprofiles/hermanosintimGoogle:
"Herman O. Sintim"Bio:
https://sites.google.com/site/sintimgrouphomepage/home/group-member/herman-o-sintim
PhD with David M. Hodgson (Oxford) in Organic Chemistry
Postdoc with Timothy Donohoe (Oxford) in Organic Chemistry
Postdoc with Eric Kool (Stanford) in Chemical Biology
Mean distance: 7.89 | S | N | B | C | P |
Parents
Sign in to add mentor| David M. Hodgson | grad student | 2002 | Oxford |
| Timothy J. Donohoe | post-doc | 2002-2004 | Oxford |
| Eric T. Kool | post-doc | 2004-2006 | Stanford |
Children
Sign in to add trainee| Christopher R. Vickery | research assistant | ||
| Modi Wang | post-doc | 2017- | Purdue (BME Tree) |
| Dimpy Kalia | post-doc | 2012-2013 | University of Maryland |
| Clinton Gregory Mikek | post-doc | 2017-2018 | Purdue |
BETA: Related publications
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Publications
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| Morse J, Wang D, Mei S, et al. (2024) Chloride Homeostasis Regulates cGAS-STING Signaling. Biorxiv : the Preprint Server For Biology |
| Onyedibe KI, Mohallem R, Wang M, et al. (2023) Proteomic and phosphoproteomic analyses of Jurkat T-cell treated with 2'3' cGAMP reveals various signaling axes impacted by cyclic dinucleotides. Journal of Proteomics. 279: 104869 |
| Wang M, Chaudhuri R, Ong WWS, et al. (2021) c-di-GMP Induces COX-2 Expression in Macrophages in a STING-Independent Manner. Acs Chemical Biology |
| Dayal N, Wang M, Sintim HO. (2020) HSD1787, a Tetrahydro-3-Pyrazolo[4,3-]Quinoline Compound Synthesized via Povarov Reaction, Potently Inhibits Proliferation of Cancer Cell Lines at Nanomolar Concentrations. Acs Omega. 5: 23799-23807 |
| Aryal UK, Hedrick V, Onyedibe KI, et al. (2020) Global Proteomic Analyses of STING-Positive and -Negative Macrophages Reveal STING and Non-STING Differentially Regulated Cellular and Molecular Pathways. Proteomics. Clinical Applications. e1900109 |
| Huff K, Sintim H, Lescun T, et al. (2020) Effect of Novel Molecules Against Inflammation in Lipopolysaccharide (LPS)‐Stimulated Fibroblast‐Like Synoviocytes (FLS) The Faseb Journal. 34: 1-1 |
| Sintim HO, Mikek CG, Wang M, et al. (2019) Interrupting cyclic dinucleotide-cGAS-STING axis with small molecules. Medchemcomm. 10: 1999-2023 |
| Onyedibe KI, Wang M, Sintim HO. (2019) ENPP1, an Old Enzyme with New Functions, and Small Molecule Inhibitors-A STING in the Tale of ENPP1. Molecules (Basel, Switzerland). 24 |
| Dayal N, Opoku-Temeng C, Mohammad H, et al. (2019) Inhibitors of Intracellular Gram-positive Bacteria Growth Synthesized via Povarov-Doebner Reactions. Acs Infectious Diseases |
| Dayal N, Mikek CG, Hernandez D, et al. (2019) Potently inhibiting cancer cell migration with novel 3H-pyrazolo[4,3-f]quinoline boronic acid ROCK inhibitors. European Journal of Medicinal Chemistry. 180: 449-456 |