William H. Gmeiner
Affiliations: | Molecular Genetics & Genomics | Wake Forest University, Winston-Salem, NC, United States |
Area:
Biochemistry, Medicine and Surgery, Oncology, NanotechnologyGoogle:
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Publications
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Gmeiner WH. (2020) Chemistry of Fluorinated Pyrimidines in the Era of Personalized Medicine. Molecules. 25: 3438 |
Gmeiner WH, Miller LD, Chou JW, et al. (2020) Dysregulated Pyrimidine Biosynthesis Contributes to 5-FU Resistance in SCLC Patient-Derived Organoids but Response to a Novel Polymeric Fluoropyrimidine, CF10. Cancers. 12 |
Thaker S, Gmeiner WH, Ji P, et al. (2020) Abstract 1842: F10 and 5-fluorouracil: Chemotherapeutic potential of F10 in alleviating colon cancer racial health disparity Cancer Research. 80: 1842-1842 |
Mani C, Gmeiner W, Palle K. (2019) Abstract 2087: Mechanistic studies reveal novel molecular insights on anticancer properties of F10 compound in human colon cancer cells Cancer Research. 79: 2087-2087 |
Gmeiner WH, Manandhar M, Hinds AM, et al. (2019) Abstract 2079: Enhanced potency of the polymeric fluoropyrimidine CF10 to KRAS-mutant colorectal cancer cells Cancer Research. 79: 2079-2079 |
Mani C, Pai S, Papke CM, et al. (2018) Thymineless Death by the Fluoropyrimidine Polymer F10 Involves Replication Fork Collapse and Is Enhanced by Chk1 Inhibition. Neoplasia (New York, N.Y.). 20: 1236-1245 |
Melvin RL, Thompson WG, Godwin RC, et al. (2017) MutS's Multi-Domain Allosteric Response to Three DNA Damage Types Revealed by Machine Learning. Frontiers in Physics. 5 |
Ghosh S, Mallick S, Das U, et al. (2017) Curcumin stably interacts with DNA hairpin through minor groove binding and demonstrates enhanced cytotoxicity in combination with FdU nucleotides. Biochimica Et Biophysica Acta |
Godwin RC, Gmeiner WH, Salsbury FR. (2017) All-atom molecular dynamics comparison of disease-associated zinc fingers. Journal of Biomolecular Structure & Dynamics. 1-14 |
Melvin RL, Gmeiner WH, Salsbury FR. (2017) All-atom MD indicates ion-dependent behavior of therapeutic DNA polymer. Physical Chemistry Chemical Physics : Pccp |