Chaitanya A. Patwardhan, Ph.D.

Affiliations: 
2014 Georgia Regents University 
Area:
Biochemistry, Oncology, General
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"Chaitanya Patwardhan"
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Ahmed Chadli grad student 2014 Georgia Regents University
 (Development of novel inhibitors of HSP90 chaperoning machinery as powerful anti-cancer drugs.)
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Publications

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Patwardhan CA, Kommalapati VK, Llbiyi T, et al. (2023) Capsaicin binds the N-terminus of Hsp90, induces lysosomal degradation of Hsp70, and enhances the anti-tumor effects of 17-AAG (Tanespimycin). Scientific Reports. 13: 13790
Eisa NH, Jilani Y, Kainth K, et al. (2019) The co-chaperone UNC45A is essential for the expression of mitotic kinase NEK7 and tumorigenesis. The Journal of Biological Chemistry
Patwardhan CA, Alfa E, Lu S, et al. (2015) Progesterone receptor chaperone complex-based high-throughput screening assay: identification of capsaicin as an inhibitor of the Hsp90 machine. Journal of Biomolecular Screening. 20: 223-9
Paul A, Garcia YA, Zierer B, et al. (2014) The cochaperone SGTA (small glutamine-rich tetratricopeptide repeat-containing protein alpha) demonstrates regulatory specificity for the androgen, glucocorticoid, and progesterone receptors. The Journal of Biological Chemistry. 289: 15297-308
Patwardhan CA, Peterson LB, Blagg B, et al. (2014) Abstract 3197: Gedunin inactivates the co-chaperone p23 causing cancer cell death by apoptosis Cancer Research. 74: 3197-3197
Patwardhan CA, Fauq A, Peterson LB, et al. (2013) Gedunin inactivates the co-chaperone p23 protein causing cancer cell death by apoptosis. The Journal of Biological Chemistry. 288: 7313-25
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