Joslyn K. Brunelle, Ph.D.

Affiliations: 
2005 Northwestern University, Evanston, IL 
Area:
Molecular Biology
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"Joslyn Brunelle"
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Navdeep S. Chandel grad student 2005 Northwestern
 (Mechanisms of oxygen deprivation induced cell death.)
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Brunelle JK, Zhang B. (2010) Apoptosis assays for quantifying the bioactivity of anticancer drug products. Drug Resistance Updates : Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy. 13: 172-9
Brunelle JK, Ryan J, Yecies D, et al. (2009) MCL-1-dependent leukemia cells are more sensitive to chemotherapy than BCL-2-dependent counterparts. The Journal of Cell Biology. 187: 429-42
Brunelle JK, Letai A. (2009) Control of mitochondrial apoptosis by the Bcl-2 family. Journal of Cell Science. 122: 437-41
Brunelle JK, Shroff EH, Perlman H, et al. (2007) Loss of Mcl-1 protein and inhibition of electron transport chain together induce anoxic cell death. Molecular and Cellular Biology. 27: 1222-35
Lee VY, Schroedl C, Brunelle JK, et al. (2005) Bleomycin induces alveolar epithelial cell death through JNK-dependent activation of the mitochondrial death pathway. American Journal of Physiology. Lung Cellular and Molecular Physiology. 289: L521-8
Brunelle JK, Bell EL, Quesada NM, et al. (2005) Oxygen sensing requires mitochondrial ROS but not oxidative phosphorylation. Cell Metabolism. 1: 409-14
DeHahn KC, Gonzales M, Gonzalez AM, et al. (2004) The alpha4 laminin subunit regulates endothelial cell survival. Experimental Cell Research. 294: 281-9
Brunelle JK, Santore MT, Budinger GR, et al. (2004) c-Myc sensitization to oxygen deprivation-induced cell death is dependent on Bax/Bak, but is independent of p53 and hypoxia-inducible factor-1. The Journal of Biological Chemistry. 279: 4305-12
Brunelle JK, Chandel NS. (2002) Oxygen deprivation induced cell death: an update. Apoptosis : An International Journal On Programmed Cell Death. 7: 475-82
McClintock DS, Santore MT, Lee VY, et al. (2002) Bcl-2 family members and functional electron transport chain regulate oxygen deprivation-induced cell death. Molecular and Cellular Biology. 22: 94-104
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