Frank D. Weinberg, Ph.D.

Affiliations: 
2010 Integrated Graduate Program in the Life Sciences Northwestern University, Evanston, IL 
Area:
Cell Biology
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"Frank Weinberg"
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Parents

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Navdeep S. Chandel grad student 2010 Northwestern
 (Mitochondrial metabolism and reactive oxygen species are required for tumorigenesis.)
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Publications

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Weinberg F, Ramnath N, Nagrath D. (2019) Reactive Oxygen Species in the Tumor Microenvironment: An Overview. Cancers. 11
Bera S, Weinberg F, Ekoue DN, et al. (2014) Natural allelic variations in glutathione peroxidase-1 affect its subcellular localization and function. Cancer Research. 74: 5118-26
Weinberg F, Hamanaka R, Wheaton WW, et al. (2010) Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity. Proceedings of the National Academy of Sciences of the United States of America. 107: 8788-93
Weinberg F, Chandel NS. (2009) Mitochondrial metabolism and cancer. Annals of the New York Academy of Sciences. 1177: 66-73
Weinberg F, Chandel NS. (2009) Reactive oxygen species-dependent signaling regulates cancer. Cellular and Molecular Life Sciences : Cmls. 66: 3663-73
Emerling BM, Weinberg F, Snyder C, et al. (2009) Hypoxic activation of AMPK is dependent on mitochondrial ROS but independent of an increase in AMP/ATP ratio. Free Radical Biology & Medicine. 46: 1386-91
Klimova TA, Bell EL, Shroff EH, et al. (2009) Hyperoxia-induced premature senescence requires p53 and pRb, but not mitochondrial matrix ROS. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 783-94
Emerling BM, Weinberg F, Liu JL, et al. (2008) PTEN regulates p300-dependent hypoxia-inducible factor 1 transcriptional activity through Forkhead transcription factor 3a (FOXO3a). Proceedings of the National Academy of Sciences of the United States of America. 105: 2622-7
Lin X, David CA, Donnelly JB, et al. (2008) A chemical genomics screen highlights the essential role of mitochondria in HIF-1 regulation. Proceedings of the National Academy of Sciences of the United States of America. 105: 174-9
Rizvi MA, Ghias K, Davies KM, et al. (2006) Enzastaurin (LY317615), a protein kinase Cbeta inhibitor, inhibits the AKT pathway and induces apoptosis in multiple myeloma cell lines. Molecular Cancer Therapeutics. 5: 1783-9
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