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Issa E. Amara, Ph.D.

Affiliations: 
2013 Faculty of Pharmacy and Pharmaceutical Sciences University of Alberta, Edmonton, Alberta, Canada 
Area:
Pharmacy
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Ayman El-Kadi grad student 2013 University of Alberta
 (Modulation of aryl hydrocarbon receptor-regulated genes by mercury.)

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Amara IE, Elshenawy OH, Abdelrady M, et al. (2014) Acute mercury toxicity modulates cytochrome P450, soluble epoxide hydrolase and their associated arachidonic acid metabolites in C57Bl/6 mouse heart. Toxicology Letters. 226: 53-62
Amara IE, Anwar-Mohamed A, El-Kadi AO. (2013) Posttranslational mechanisms modulating the expression of the cytochrome P450 1A1 gene by methylmercury in HepG2 cells: a role of heme oxygenase-1. Toxicology Letters. 219: 239-47
Abdelhamid G, Amara IE, Anwar-Mohamed A, et al. (2013) Modulation of cytochrome P450 1 (Cyp1) by vanadium in hepatic tissue and isolated hepatocyte of C57BL/6 mice. Archives of Toxicology. 87: 1531-43
Anwar-Mohamed A, Abdelhamid G, Amara IE, et al. (2013) Differential modulation of cytochrome P450 1a1 by arsenite in vivo and in vitro in C57BL/6 mice. Free Radical Biology & Medicine. 58: 52-63
Amara IE, Anwar-Mohamed A, Abdelhamid G, et al. (2013) Mercury modulates the cytochrome P450 1a1, 1a2 and 1b1 in C57BL/6J mice: in vivo and in vitro studies. Toxicology and Applied Pharmacology. 266: 419-29
Abdelhamid G, Amara IE, Anwar-Mohamed A, et al. (2013) Modulation of aryl hydrocarbon receptor-regulated genes by acute administration of ammonium metavanadate in kidney, lung and heart of C57BL/6 mice. Journal of Applied Toxicology : Jat. 33: 1230-40
Amara IE, Anwar-Mohamed A, Abdelhamid G, et al. (2012) Effect of mercury on aryl hydrocarbon receptor-regulated genes in the extrahepatic tissues of C57BL/6 mice. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 50: 2325-34
Anwar-Mohamed A, Abdelhamid G, Amara IE, et al. (2012) Differential modulation of aryl hydrocarbon receptor regulated enzymes by arsenite in the kidney, lung, and heart of C57BL/6 mice. Archives of Toxicology. 86: 897-910
Amara IE, El-Kadi AO. (2011) Transcriptional modulation of the NAD(P)H:quinone oxidoreductase 1 by mercury in human hepatoma HepG2 cells. Free Radical Biology & Medicine. 51: 1675-85
Amara IE, Anwar-Mohamed A, El-Kadi AO. (2010) Mercury modulates the CYP1A1 at transcriptional and posttranslational levels in human hepatoma HepG2 cells. Toxicology Letters. 199: 225-33
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