Ryan J. Ice, Ph.D.

Affiliations: 
2014 School of Medicine West Virginia University, Morgantown, WV, United States 
Area:
Oncology, Biochemistry, Pharmacology
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Elena N. Pugacheva grad student 2014 West Virginia University
 (Implications of NEDD9 on AURKA activity: a biomarker for sensitization and therapeutic target in solid tumors.)
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Publications

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Purazo ML, Ice RJ, Shimpi R, et al. (2023) NEDD9 Overexpression Causes Hyperproliferation of Luminal Cells and Cooperates with HER2 Oncogene in Tumor Initiation: A Novel Prognostic Marker in Breast Cancer. Cancers. 15
Sidorov M, Dighe P, Woo RWL, et al. (2023) Dual Targeting of EGFR and MTOR Pathways Inhibits Glioblastoma Growth by Modulating the Tumor Microenvironment. Cells. 12
Chen M, Jian D, Sidorov M, et al. (2022) Pitfalls and Rewards of Setting Up a Liquid Biopsy Approach for the Detection of Driver Mutations in Circulating Tumor DNAs: Our Institutional Experience. Journal of Personalized Medicine. 12
Saqub H, Proetsch-Gugerbauer H, Bezrookove V, et al. (2020) Dinaciclib, a cyclin-dependent kinase inhibitor, suppresses cholangiocarcinoma growth by targeting CDK2/5/9. Scientific Reports. 10: 18489
Pugacheva EN, Kozyreva V, Kiseleva A, et al. (2017) Abstract 1084: Combination of eribulin and AURKA inhibitor prevents metastatic colonization and eradicates established metastases in breast cancer Cancer Research. 77: 1084-1084
Kozyreva VK, Kiseleva A, Ice RJ, et al. (2016) Combination of Eribulin and Aurora A inhibitor MLN8237 prevents metastatic colonization and induces cytotoxic autophagy in breast cancer. Molecular Cancer Therapeutics
Ice R, Kiseleva A, Loskutov Y, et al. (2016) Abstract B20: Development of metastatic patient-derived xenografts (PDXs) for accurate assessment of anti-metastatic therapeutics in pre-clinical settings Clinical Cancer Research. 22
Park J, Schlederer M, Schreiber M, et al. (2015) AF1q is a novel TCF7 co-factor which activates CD44 and promotes breast cancer metastasis. Oncotarget
Lin CC, Sharma SB, Farrugia MK, et al. (2015) Kruppel-like factor 4 signals through microRNA-206 to promote tumor initiation and cell survival. Oncogenesis. 4: e155
Kozyulina PY, Loskutov YV, Kozyreva VK, et al. (2015) Prometastatic NEDD9 Regulates Individual Cell Migration via Caveolin-1-Dependent Trafficking of Integrins. Molecular Cancer Research : McR. 13: 423-38
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