Zachary R. Hartman, Ph.D.
Affiliations: | 2013 | School of Medicine | West Virginia University, Morgantown, WV, United States |
Area:
Biochemistry, Cell Biology, OncologyGoogle:
"Zachary Hartman"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Yehenew M. Agazie | grad student | 2013 | West Virginia University | |
| (Exploring the mechanism of SHP2 and EGFR/HER2 cooperation in breast cancer cell signaling.) | ||||
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| Butler W, Xu L, Zhou Y, et al. (2023) Oncofetal protein glypican-3 is a biomarker and critical regulator of function for neuroendocrine cells in prostate cancer. The Journal of Pathology |
| Hartman Z, Geldenhuys WJ, Agazie YM. (2020) Novel Small-Molecule Inhibitor for the Oncogenic Tyrosine Phosphatase SHP2 with Anti-Breast Cancer Cell Effects. Acs Omega. 5: 25113-25124 |
| Hartman Z, Geldenhuys WJ, Agazie YM. (2020) A specific amino acid context in EGFR and HER2 phosphorylation sites enables selective binding to the active site of Src homology phosphatase 2 (SHP2). The Journal of Biological Chemistry |
| Agazie Y, Hartman Z. (2020) Abstract P3-10-20: Targeting the tyrosine phosphatase SHP2 is efficacious against HER2-positive breast cancer Cancer Research. 80 |
| Agazie Y, Hartman Z. (2019) Abstract P6-20-17: Targeting SHP2 for the treatment of HER2-positive breast cancer Cancer Research. 79 |
| Osada T, Morse MA, Hobeika A, et al. (2017) Vaccination targeting human HER3 alters the phenotype of infiltrating T cells and responses to immune checkpoint inhibition. Oncoimmunology. 6: e1315495 |
| Hartman ZR, Schaller MD, Agazie YM. (2013) The tyrosine phosphatase SHP2 regulates focal adhesion kinase to promote EGF-induced lamellipodia persistence and cell migration. Molecular Cancer Research : McR. 11: 651-64 |
| Hartman Z, Zhao H, Agazie YM. (2012) HER2 stabilizes EGFR and itself by altering autophosphorylation patterns in a manner that overcomes regulatory mechanisms and promotes proliferative and transformation signaling. Oncogene. 32: 4169-80 |
| Matalka F, Hartman Z, Agazie YM. (2011) Abstract 238: Inhibition of SHP2 abolishes mammary tumorigenesis in mice Cancer Research. 71: 238-238 |
| Agazie Y, Matalka F, Hartman Z. (2011) P3-01-15: The Role of Src Homology Phosphotyrosyl Phosphatase-2 in Basal-Type/Triple-Negative Breast Cancer – Implications for Targeted Therapy. Cancer Research. 71 |