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Felice Tirone, Laurea (1979) and PhD (obtained in 1987)

Affiliations: 
Cell Biology and Neurobiology National Research Council, Rome Italy 
Area:
Neurobiology
Website:
http://www.inmm.cnr.it/tirone/
Google:
"Felice Tirone"
Bio:

Felice Tirone at the beginning of his career has performed studies of neurochemistry at the University of Milan, Department of Pharmacology, during his experimental thesis for the degree in Biological Sciences and for a period as Ph.D student, in the laboratory of A.Groppetti. During this period he has contributed to clarify issues concerning the function of neuronal dopaminergic and serotoninergic circuits of central nervous system.

Since 1986 he has developed the interest for gene regulation during the development of the nervous system, a topic that he investigated for three and half years (end 1985 to beginning 1989) in the laboratory of Eric Shooter, at the Dept. of Neurobiology della Stanford University, USA.

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Mean distance: 15.79 (cluster 11)
 
Cross-listing: Neurotree - Cell Biology Tree

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Parents

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Eric M. Shooter post-doc 1985-1989 Stanford University Medical School (Neurotree)

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Publications

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Micheli L, Creanza TM, Ceccarelli M, et al. (2021) Transcriptome Analysis in a Mouse Model of Premature Aging of Dentate Gyrus: Rescue of Alpha-Synuclein Deficit by Virus-Driven Expression or by Running Restores the Defective Neurogenesis. Frontiers in Cell and Developmental Biology. 9: 696684
Presutti D, Ceccarelli M, Micheli L, et al. (2018) Tis21-gene therapy inhibits medulloblastoma growth in a murine allograft model. Plos One. 13: e0194206
Micheli L, Ceccarelli M, Gioia R, et al. (2017) Terminal Differentiation of Adult Hippocampal Progenitor Cells Is a Step Functionally Dissociable from Proliferation and Is Controlled by Tis21, Id3 and NeuroD2. Frontiers in Cellular Neuroscience. 11: 186
Micheli L, D'Andrea G, Leonardi L, et al. (2016) HDAC1, HDAC4 and HDAC9 Bind to PC3/Tis21/Btg2 and Are Required for its Inhibition of Cell Cycle Progression and Cyclin D1 Expression. Journal of Cellular Physiology
Micheli L, Ceccarelli M, Farioli-Vecchioli S, et al. (2015) Control of the Normal and Pathological Development of Neural Stem and Progenitor Cells by the PC3/Tis21/Btg2 and Btg1 Genes. Journal of Cellular Physiology. 230: 2881-90
Micheli L, Leonardi L, Conti F, et al. (2011) PC4/Tis7/IFRD1 stimulates skeletal muscle regeneration and is involved in myoblast differentiation as a regulator of MyoD and NF-kappaB. The Journal of Biological Chemistry. 286: 5691-707
Farioli-Vecchioli S, Saraulli D, Costanzi M, et al. (2009) Impaired terminal differentiation of hippocampal granule neurons and defective contextual memory in PC3/Tis21 knockout mice. Plos One. 4: e8339
Farioli-Vecchioli S, Tanori M, Micheli L, et al. (2007) Inhibition of medulloblastoma tumorigenesis by the antiproliferative and pro-differentiative gene PC3. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 2215-25
Micheli L, Leonardi L, Conti F, et al. (2005) PC4 coactivates MyoD by relieving the histone deacetylase 4-mediated inhibition of myocyte enhancer factor 2C. Molecular and Cellular Biology. 25: 2242-59
Canzoniere D, Farioli-Vecchioli S, Conti F, et al. (2004) Dual control of neurogenesis by PC3 through cell cycle inhibition and induction of Math1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 3355-69
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