Hendrik Luesch
Affiliations: | University of Florida, Gainesville, Gainesville, FL, United States |
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Parents
Sign in to add mentor| Richard E. Moore | grad student | 1997-2002 | University of Hawai'i at Manoa | |
| (The search for new anticancer drugs from marine cyanobacteria and investigations on the biosynthesis of cyanobacterial metabolites.) | ||||
| Peter G. Schultz | post-doc | 2002-2005 | Scripps Research Institute | |
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Publications
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| Kallifidas D, Dhakal D, Chen M, et al. (2024) Biosynthesis of Dolastatin 10 in Marine Cyanobacteria, a Prototype for Multiple Approved Cancer Drugs. Organic Letters |
| Tang Q, Ratnayake R, Seabra G, et al. (2023) Morphological Profiling for Drug Discovery in the Era of Deep Learning. Arxiv |
| Atanasova KR, Perkins CM, Ratnayake R, et al. (2023) Epigenetic Small-Molecule Screen for Inhibition and Reversal of Acinar Ductal Metaplasia in Mouse Pancreatic Organoids. Biorxiv : the Preprint Server For Biology |
| Al-Awadhi FH, Simon EF, Liu N, et al. (2023) Discovery and Anti-Inflammatory Activity of a Cyanobacterial Fatty Acid Targeting the Keap1/Nrf2 Pathway. Marine Drugs. 21 |
| Kokkaliari S, Luo D, Paul VJ, et al. (2023) Isolation and Biological Activity of Iezoside and Iezoside B, SERCA Inhibitors from Floridian Marine Cyanobacteria. Marine Drugs. 21 |
| Luo D, Ratnayake R, Atanasova KR, et al. (2023) Targeted and Functional Genomics Approaches to the Mechanism of Action of Lagunamide D, a Mitochondrial Cytotoxin from Marine Cyanobacteria. Biochemical Pharmacology. 115608 |
| Dhakal D, Kallifidas D, Chen M, et al. (2023) Heterologous Production of the C33-C45 Polyketide Fragment of Anticancer Apratoxins in a Cyanobacterial Host. Organic Letters |
| Dhakal D, Kokkaliari S, Rubin GM, et al. (2022) Biosynthesis of Lyngbyastatins 1 and 3, Cytotoxic Depsipeptides from an sp. Marine Cyanobacterium. Journal of Natural Products |
| da Silva L, Jiang J, Perkins C, et al. (2022) Pharmacological inhibition and reversal of pancreatic acinar ductal metaplasia. Cell Death Discovery. 8: 378 |
| Pohl MO, Martin-Sancho L, Ratnayake R, et al. (2022) Sec61 Inhibitor Apratoxin S4 Potently Inhibits SARS-CoV-2 and Exhibits Broad-Spectrum Antiviral Activity. Acs Infectious Diseases |