Heiko Wurdak

Affiliations: 
University of Leeds, UK 
Area:
Stem cell and tumor biology
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"Heiko Wurdak"
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Publications

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Andreou T, Williams J, Brownlie RJ, et al. (2021) Hematopoietic stem cell gene therapy targeting TGFβ enhances the efficacy of irradiation therapy in a preclinical glioblastoma model. Journal For Immunotherapy of Cancer. 9
Alshawli AS, Wurdak H, Wood IC, et al. (2020) Histone deacetylase inhibitors induce medulloblastoma cell death independent of HDACs recruited in REST repression complexes. Molecular Genetics & Genomic Medicine. e1429
Close HJ, Stead LF, Nsengimana J, et al. (2019) Expression profiling of single cells and patient cohorts identifies multiple immunosuppressive pathways and an altered NK cell phenotype in glioblastoma. Clinical and Experimental Immunology
da Silva B, Irving BK, Polson ES, et al. (2019) Chemically-induced neurite-like outgrowth reveals multicellular network function in patient-derived glioblastoma cells. Journal of Cell Science
Lucki NC, Villa GR, Vergani N, et al. (2019) A cell type-selective apoptosis-inducing small molecule for the treatment of brain cancer. Proceedings of the National Academy of Sciences of the United States of America
Haynes HR, Scott HL, Killick-Cole CL, et al. (2018) shRNA-mediated PPARα knockdown in human glioma stem cells reduces in vitro proliferation and inhibits orthotopic xenograft tumour growth. The Journal of Pathology
Polson ES, Kuchler VB, Abbosh C, et al. (2018) KHS101 disrupts energy metabolism in human glioblastoma cells and reduces tumor growth in mice. Science Translational Medicine. 10
da Silva B, Mathew RK, Polson ES, et al. (2018) Spontaneous Glioblastoma Spheroid Infiltration of Early-Stage Cerebral Organoids Models Brain Tumor Invasion. Slas Discovery : Advancing Life Sciences R & D. 2472555218764623
Samson A, Scott KJ, Taggart D, et al. (2018) Intravenous delivery of oncolytic reovirus to brain tumor patients immunologically primes for subsequent checkpoint blockade. Science Translational Medicine. 10
King HO, Brend T, Payne HL, et al. (2017) RAD51 Is a Selective DNA Repair Target to Radiosensitize Glioma Stem Cells. Stem Cell Reports. 8: 125-139
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