Christian J. Leumann
Affiliations: | University of Bern, Bern, Bern, Switzerland |
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Parents
Sign in to add mentor| Albert Jakob Eschenmoser | grad student | 1982-1986 | ETH Zürich |
| Peter G. Schultz | post-doc | 1987-1988 | UC Berkeley College of Chemistry |
Children
Sign in to add trainee| Michael H. Räz | research assistant | 2011-2014 | University of Bern |
| Jay Herath | grad student | UBC | |
| Marcel Hollenstein | grad student | ||
| Dae-Ro Ahn | grad student | 2000-2003 | University of Berne |
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Publications
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| Evéquoz D, Verhaart IEC, van de Vijver D, et al. (2021) 7',5'-alpha-bicyclo-DNA: new chemistry for oligonucleotide exon splicing modulation therapy. Nucleic Acids Research |
| Röthlisberger P, Levi-Acobas F, Leumann CJ, et al. (2020) Enzymatic synthesis of biphenyl-DNA oligonucleotides. Bioorganic & Medicinal Chemistry. 115487 |
| Levi-Acobas F, Katolik A, Röthlisberger P, et al. (2019) Compatibility of 5-ethynyl-2'F-ANA UTP with in vitro selection for the generation of base-modified, nuclease resistant aptamers. Organic & Biomolecular Chemistry |
| Imbert M, Blandel F, Leumann C, et al. (2019) Lowering Mutant Huntingtin Using Tricyclo-DNA Antisense Oligonucleotides As a Therapeutic Approach for Huntington's Disease. Nucleic Acid Therapeutics. 29: 256-265 |
| Diafa S, Evéquoz D, Leumann CJ, et al. (2019) Synthesis and Enzymatic Characterization of Sugar-Modified Nucleoside Triphosphate Analogs. Methods in Molecular Biology (Clifton, N.J.). 1973: 1-13 |
| Istrate A, Johannsen S, Istrate A, et al. (2019) NMR solution structure of tricyclo-DNA containing duplexes: insight into enhanced thermal stability and nuclease resistance. Nucleic Acids Research |
| Frei S, Katolik AK, Leumann CJ. (2019) Synthesis, biophysical properties, and RNase H activity of 6'-difluoro[4.3.0]bicyclo-DNA. Beilstein Journal of Organic Chemistry. 15: 79-88 |
| Frei S, Istrate A, Leumann CJ. (2018) 6'-Fluoro[4.3.0]bicyclo nucleic acid: synthesis, biophysical properties and molecular dynamics simulations. Beilstein Journal of Organic Chemistry. 14: 3088-3097 |
| Hari Y, Leumann CJ, Schürch S. (2017) What Hinders Electron Transfer Dissociation (ETD) of DNA Cations? Journal of the American Society For Mass Spectrometry |
| Robin V, Griffith G, Carter JL, et al. (2017) Efficient SMN Rescue following Subcutaneous Tricyclo-DNA Antisense Oligonucleotide Treatment. Molecular Therapy. Nucleic Acids. 7: 81-89 |