Christopher Michael Browne
Affiliations: | Harvard Medical School/Dana-Farber Cancer Institute, Boston, MA, United States |
Area:
Proteomics, Covalent Inhibitors, KinasesGoogle:
"Christopher Browne"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Andrew J. Link | grad student | 2007-2013 | Vanderbilt | |
| (Genetic and biochemical analysis of the interaction between the yeast fatty acid synthesis enzyme ybr159w and the translation initiation complex eIF2B.) | ||||
| Nathanael Gray | post-doc | 2014- | Harvard Medical School/Dana-Farber Cancer Institute | |
| Jarrod A. Marto | post-doc | 2014- | Harvard Medical School/Dana-Farber Cancer Institute | |
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Publications
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| Dubiella C, Pinch BJ, Koikawa K, et al. (2021) Sulfopin is a covalent inhibitor of Pin1 that blocks Myc-driven tumors in vivo. Nature Chemical Biology |
| Sun M, Shen B, Li W, et al. (2020) A time-resolved cryo-EM Study of S. cerevisiae 80S Ribosome Protein Composition in Response to a Change in Carbon Source. Proteomics. e2000125 |
| Pinch BJ, Doctor ZM, Nabet B, et al. (2020) Identification of a potent and selective covalent Pin1 inhibitor. Nature Chemical Biology |
| Sivakumaren SC, Shim H, Zhang T, et al. (2020) Targeting the PI5P4K Lipid Kinase Family in Cancer Using Covalent Inhibitors. Cell Chemical Biology |
| Link AJ, Niu X, Weaver CM, et al. (2020) Targeted identification of protein interactions in eukaryotic mRNA translation. Proteomics. e1900177 |
| Rao S, Gurbani D, Du G, et al. (2019) Leveraging Compound Promiscuity to Identify Targetable Cysteines within the Kinome. Cell Chemical Biology |
| Ferguson FM, Doctor ZM, Ficarro SB, et al. (2019) Discovery of Covalent CDK14 Inhibitors with Pan-TAIRE Family Specificity. Cell Chemical Biology |
| Pinch B, Doctor Z, Browne CM, et al. (2019) Abstract 2757: Discovery and characterization of covalent Pin1 inhibitors targeted to an active site cysteine Cancer Research. 79: 2757-2757 |
| Browne CM, Jiang B, Ficarro SB, et al. (2018) A Chemoproteomic Strategy for Direct and Proteome-wide Covalent Inhibitor Target-site Identification. Journal of the American Chemical Society |
| Gerbasi VR, Browne CM, Samir P, et al. (2018) Critical Role for Saccharomyces cerevisiae Asc1p in Translational Initiation at Elevated Temperatures. Proteomics. e1800208 |