Yao Liu
Affiliations: | Dana-Farber Cancer Institute and Harvard Medical School, USA |
Area:
cancer researchGoogle:
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Chen M, Yin B, Liu Y, et al. (2024) ARRDC3 regulates the targeted therapy sensitivity of clear cell renal cell carcinoma by promoting AXL degradation. Cell Cycle (Georgetown, Tex.). 1-14 |
Song Y, Malpica L, Cai Q, et al. (2023) Golidocitinib, a selective JAK1 tyrosine-kinase inhibitor, in patients with refractory or relapsed peripheral T-cell lymphoma (JACKPOT8 Part B): a single-arm, multinational, phase 2 study. The Lancet. Oncology |
Arwood ML, Liu Y, Harkins SK, et al. (2023) New scaffolds for type II JAK2 inhibitors overcome the acquired G993A resistance mutation. Cell Chemical Biology |
Lu W, Liu Y, Gao Y, et al. (2023) Development of a Covalent Inhibitor of c-Jun N-Terminal Protein Kinase (JNK) 2/3 with Selectivity over JNK1. Journal of Medicinal Chemistry. 66: 3356-3371 |
Fan M, Lu W, Che J, et al. (2022) Covalent disruptor of YAP-TEAD association suppresses defective hippo signaling. Elife. 11 |
Zhang S, Peng X, Li X, et al. (2021) BKM120 sensitizes glioblastoma to the PARP inhibitor rucaparib by suppressing homologous recombination repair. Cell Death & Disease. 12: 546 |
Jiang T, Wang G, Liu Y, et al. (2021) Development of small-molecule tropomyosin receptor kinase (TRK) inhibitors for fusion cancers. Acta Pharmaceutica Sinica. B. 11: 355-372 |
Liu Y, Hao M, Leggett A, et al. (2020) Discovery of MFH290: A Potent and Highly Selective Covalent Inhibitor for Cyclin-Dependent Kinase 12/13. Journal of Medicinal Chemistry |
Wang G, Zhao Y, Liu Y, et al. (2020) Discovery of a novel dual-target inhibitor of ERK1 and ERK5 that induces regulated cell death to overcome compensatory mechanism in specific tumor types. Journal of Medicinal Chemistry |
Kurppa KJ, Liu Y, To C, et al. (2020) Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway. Cancer Cell. 37: 104-122.e12 |