Zhixiang He
Affiliations: | 2013-2016 | School of Life Sciences, Xiamen University |
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Sign in to add mentor| Xianming DENG | grad student | 2013-2016 | School of Life Sciences, Xiamen University |
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| Gui F, Jiang B, Jiang J, et al. (2024) Acute BRCAness Induction and AR Signaling Blockage through CDK12/7/9 Degradation Enhances PARP Inhibitor Sensitivity in Prostate Cancer. Biorxiv : the Preprint Server For Biology |
| Ji W, Du G, Jiang J, et al. (2024) Discovery of bivalent small molecule degraders of cyclin-dependent kinase 7 (CDK7). European Journal of Medicinal Chemistry. 276: 116613 |
| Liu HY, Li Z, Reindl T, et al. (2024) Broad-spectrum activity against mosquito-borne flaviviruses achieved by a targeted protein degradation mechanism. Nature Communications. 15: 5179 |
| Li Z, Liu HY, He Z, et al. (2024) Discovery of Potent Degraders of the Dengue Virus Envelope Protein. Biorxiv : the Preprint Server For Biology |
| Arwood ML, Liu Y, Harkins SK, et al. (2023) New scaffolds for type II JAK2 inhibitors overcome the acquired G993A resistance mutation. Cell Chemical Biology |
| Lu W, Liu Y, Gao Y, et al. (2023) Development of a Covalent Inhibitor of c-Jun N-Terminal Protein Kinase (JNK) 2/3 with Selectivity over JNK1. Journal of Medicinal Chemistry. 66: 3356-3371 |
| Fan M, Lu W, Che J, et al. (2022) Covalent disruptor of YAP-TEAD association suppresses defective hippo signaling. Elife. 11 |
| Du G, Jiang J, Henning NJ, et al. (2022) Exploring the target scope of KEAP1 E3 ligase-based PROTACs. Cell Chemical Biology |
| Powell CE, Du G, Bushman JW, et al. (2021) Selective degradation-inducing probes for studying cereblon (CRBN) biology. Rsc Medicinal Chemistry. 12: 1381-1390 |
| Jiang J, Jiang B, He Z, et al. (2020) Discovery of Covalent MKK4/7 Dual Inhibitor. Cell Chemical Biology |