Ari J. Firestone
Affiliations: | Calico Life Sciences, LLC |
Area:
Oncology, Cell signaling, Chemical biologyGoogle:
"Ari Firestone"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| James K. Chen | grad student | 2003-2011 | Stanford |
| Kevin M. Shannon | post-doc | 2012-2015 | UCSF (Cell Biology Tree) |
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Publications
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| Choy L, Norris S, Wu X, et al. (2024) Inhibition of Aurora kinase induces endogenous retroelements to induce a type I/III interferon response via RIG-I. Cancer Research Communications |
| Suciu RM, Luvaga IK, Hazeen A, et al. (2021) Chemical proteomic analysis of palmostatin beta-lactone analogs that affect N-Ras palmitoylation. Bioorganic & Medicinal Chemistry Letters. 128414 |
| Remsberg JR, Suciu RM, Zambetti NA, et al. (2021) ABHD17 regulation of plasma membrane palmitoylation and N-Ras-dependent cancer growth. Nature Chemical Biology |
| Zambetti NA, Firestone AJ, Remsberg JR, et al. (2020) Genetic disruption of N-RasG12D palmitoylation perturbs hematopoiesis and prevents myeloid transformation in mice. Blood |
| Zambetti NA, Firestone AJ, Wong JC, et al. (2020) Abstract A25: In vivo evidence validating the palmitoylation/depalmitoylation cycle as a therapeutic target in NRAS mutant hematologic cancers Molecular Cancer Research. 18 |
| Sulahian R, Kwon JJ, Walsh KH, et al. (2019) Synthetic Lethal Interaction of SHOC2 Depletion with MEK Inhibition in RAS-Driven Cancers. Cell Reports. 29: 118-134.e8 |
| Pech M, Fong LE, Villalta JE, et al. (2019) Systematic identification of cancer cell vulnerabilities to natural killer cell-mediated immune surveillance. Elife. 8 |
| Larpenteur K, Waal Ld, Wang L, et al. (2019) Abstract C022: Large scale phenotypic screening using PRISM, integrated with functional genomic screening and transcriptional profiling accelerates target identification of cytotoxic small molecules Molecular Cancer Therapeutics. 18 |
| Boudreau A, Roth J, Rong J, et al. (2019) Abstract B121: An oncogene-linked prodrug strategy in lung cancer Molecular Cancer Therapeutics. 18 |
| Burgess MR, Hwang E, Mroue R, et al. (2017) KRAS Allelic Imbalance Enhances Fitness and Modulates MAP Kinase Dependence in Cancer. Cell |