Jacqueline Sayyah, Ph.D.
Affiliations: | 2009 | University of Florida, Gainesville, Gainesville, FL, United States |
Area:
Molecular Biology, Cell Biology, Physiology BiologyGoogle:
"Jacqueline Sayyah"Mean distance: (not calculated yet)
Parents
Sign in to add mentorPeter P. Sayeski | grad student | 2009 | UF Gainesville | |
(Characterization of novel Jak2 tyrosine kinase small molecule inhibitors and sites of Jak2 phospho-regulation.) |
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Publications
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Sayyah J, Bartakova A, Nogal N, et al. (2014) The Ras-related protein, Rap1A, mediates thrombin-stimulated, integrin-dependent glioblastoma cell proliferation and tumor growth. The Journal of Biological Chemistry. 289: 17689-98 |
Sayyah J, Stupack D, Brown JH. (2013) Abstract 4101: Thrombin stimulates glioblastoma cell proliferation, adhesion and in vivo tumor growth through Rap1 activation. Cancer Research. 73: 4101-4101 |
Ortiz-Sanchez JM, Nichols SE, Sayyah J, et al. (2012) Identification of potential small molecule binding pockets on Rho family GTPases. Plos One. 7: e40809 |
Sayyah J, Gnanasambandan K, Kamarajugadda S, et al. (2011) Phosphorylation of Y372 is critical for Jak2 tyrosine kinase activation. Cellular Signalling. 23: 1806-15 |
Kiss R, Polgár T, Kirabo A, et al. (2009) Identification of a novel inhibitor of JAK2 tyrosine kinase by structure-based virtual screening. Bioorganic & Medicinal Chemistry Letters. 19: 3598-601 |
Sayyah J, Sayeski PP. (2009) Jak2 inhibitors: rationale and role as therapeutic agents in hematologic malignancies. Current Oncology Reports. 11: 117-24 |
Sayyah J, Magis A, Ostrov DA, et al. (2008) Z3, a novel Jak2 tyrosine kinase small-molecule inhibitor that suppresses Jak2-mediated pathologic cell growth. Molecular Cancer Therapeutics. 7: 2308-18 |
Godeny MD, Sayyah J, VonDerLinden D, et al. (2007) The N-terminal SH2 domain of the tyrosine phosphatase, SHP-2, is essential for Jak2-dependent signaling via the angiotensin II type AT1 receptor. Cellular Signalling. 19: 600-9 |
Sayyah J, Allen RW, Braylan RC, et al. (2007) Identification and Characterization of a Series of Novel Jak2 Small Molecule Inhibitor Compounds. Blood. 110: 539-539 |
Sayyah J, Ostrov D, Sayeski P. (2006) Identification and Characterization of a Novel Jak2 Tyrosine Kinase Inhibitor. Blood. 108: 3604-3604 |