Amy H. Andreotti

Affiliations: 
Biochemistry, Biophysics & Molecular Biology Iowa State University, Ames, IA, United States 
Area:
Nuclear magnetic resonance, Macromolecular structure and recognition
Website:
http://www.bbmb.iastate.edu/amy-andreotti/
Google:
"Amy H. Andreotti"
Bio:

http://www.bb.iastate.edu/andreotti/
http://www.bcb.iastate.edu/CV/Andreotti_CV.pdf

Mean distance: 6.93
 
SNBCP

Parents

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Daniel E. Kahne grad student 1994 Princeton
 (Part I. The effects of glycosylation on peptide backbone conformation; Part II. An NMR study of calicheamicin bound to DNA)
Stuart L. Schreiber post-doc 1994-1996 Harvard

Children

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Kristine N. Brazin grad student 2002 Iowa State
Alain T. Laederach grad student 2003 Iowa State
Lie Min grad student 2008 Iowa State
Andrew J. Severin grad student 2009 Iowa State
Scott E. Boyken grad student 2013 Iowa State
Qian Xie grad student 2014 Iowa State
Ekaterina V. Pletneva post-doc Iowa State
BETA: Related publications

Publications

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Lin DY, Kueffer LE, Juneja P, et al. (2024) Conformational heterogeneity of the BTK PHTH domain drives multiple regulatory states. Elife. 12
Kueffer LE, Lin DY, Amatya N, et al. (2023) Screening and Characterization of Allosteric Small Molecules Targeting Bruton's Tyrosine Kinase. Biochemistry
Lin DY, Kueffer LE, Juneja P, et al. (2023) Conformational heterogeneity of the BTK PHTH domain drives multiple regulatory states. Biorxiv : the Preprint Server For Biology
Lin DY, Andreotti AH. (2023) Structure of BTK kinase domain with the second-generation inhibitors acalabrutinib and tirabrutinib. Plos One. 18: e0290872
Aryal M, Lin D, Regan K, et al. (2022) The HIV-1 protein Nef activates the Tec family kinase Btk by stabilizing an intermolecular SH3-SH2 domain interaction. Science Signaling. 15: eabn8359
Brunner C, Betzler AC, Brown JR, et al. (2022) Editorial: Targeting Bruton Tyrosine Kinase. Frontiers in Cell and Developmental Biology. 10: 909655
Lowe J, Joseph RE, Andreotti AH. (2022) Conformational switches that control the TEC kinase - PLCγ signaling axis. Journal of Structural Biology: X. 6: 100061
Kueffer LE, Joseph RE, Andreotti AH. (2021) Reining in BTK: Interdomain Interactions and Their Importance in the Regulatory Control of BTK. Frontiers in Cell and Developmental Biology. 9: 655489
Joseph RE, Amatya N, Fulton DB, et al. (2020) Differential impact of BTK active site inhibitors on the conformational state of full-length BTK. Elife. 9
Amatya N, Wales TE, Kwon A, et al. (2019) Lipid-targeting pleckstrin homology domain turns its autoinhibitory face toward the TEC kinases. Proceedings of the National Academy of Sciences of the United States of America
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