David A. Powell

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2003 University of Toronto, Toronto, ON, Canada 
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"David Powell"
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Robert A. Batey grad student 2003 University of Toronto
 (Multi-component hetero Diels -Alder reaction of N-arylimines: Synthesis of functionalized tetrahydroquinolines and total synthesis of the martinelline alkaloids.)
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Publications

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Liu J, Chan J, Bryant CM, et al. (2012) Effect of acid catalysis on the direct electrophilic fluorination of ketones, ketals, and enamides using Selectfluor™ Tetrahedron Letters. 53: 2971-2975
Chen A, Dubé D, Dubé L, et al. (2010) Addressing time-dependent CYP 3A4 inhibition observed in a novel series of substituted amino propanamide renin inhibitors, a case study. Bioorganic & Medicinal Chemistry Letters. 20: 5074-9
Chen A, Bayly C, Bezençon O, et al. (2010) Design and optimization of a substituted amino propanamide series of renin inhibitors for the treatment of hypertension. Bioorganic & Medicinal Chemistry Letters. 20: 2204-9
Borduas N, Powell DA. (2008) Copper-catalyzed oxidative coupling of benzylic C-H bonds with 1,3-dicarbonyl compounds Journal of Organic Chemistry. 73: 7822-7825
Powell DA, Pelletier G. (2008) Copper triflate/t-BuOOAc-catalyzed amidation of allylic and benzylic acetates with sulfonamides Tetrahedron Letters. 49: 2495-2498
Twin H, Wen WWH, Powell DA, et al. (2007) A biogenetically inspired heterodimerization approach to the synthesis of the core structure of the alkaloid fissoldhimine Tetrahedron Letters. 48: 1841-1844
Pelletier G, Powell DA. (2006) Copper-catalyzed amidation of allylic and benzylic C-H bonds. Organic Letters. 8: 6031-4
Powell DA, Ramsden PD, Batey RA. (2003) Phase-transfer-catalyzed alkylation of guanidines by alkyl halides under biphasic conditions: a convenient protocol for the synthesis of highly functionalized guanidines. The Journal of Organic Chemistry. 68: 2300-9
Powell DA, Batey RA. (2003) Lanthanide(III)-catalyzed multi-component aza-Diels-Alder reaction of aliphatic N-arylaldimines with cyclopentadiene Tetrahedron Letters. 44: 7569-7573
Powell DA, Batey RA. (2002) Total synthesis of the alkaloids martinelline and martinellic acid via a hetero Diels-Alder multicomponent coupling reaction. Organic Letters. 4: 2913-6
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